1-Amino-3,5-dimethyladamantane

1-Amino-3,5-dimethyladamantane, CAS 19982-08-2, is a primary amine derivative of the adamantane scaffold, commercially known as Memantine and referenced under codes D 145 and AKOS BB-9600. It carries no assigned E-code. The compound is a recognised pharmaceutical intermediate with a defined EC number of 690-724-9.

Its primary application is as a key building block in the synthesis of Memantine hydrochloride, an NMDA receptor antagonist approved for treating moderate-to-severe Alzheimer's disease. The adamantane cage structure confers metabolic stability and lipophilicity, enabling effective CNS penetration in the final active pharmaceutical ingredient.

This compound is supplied as a pharmaceutical-grade solid intended for API synthesis workflows and is subject to REACH registration requirements within the EU. Procurement quantities and packaging formats are available on request. Buyers should confirm compliance with applicable Ph.Eur. or ICH guidelines for their specific manufacturing context.