1-Bromo-4-iodobenzene

1-Bromo-4-iodobenzene (CAS 589-87-7, EC 209-662-7, formula C6H4BrI) is a dihalogenated aromatic compound also referenced as p-bromoiodobenzene, p-iodobromobenzene, and NSC 8033. It carries no assigned E-code. It belongs to the pharmaceutical intermediates category and is classified under HS code 29036990.

In pharmaceutical synthesis, it serves as a selective building block in cross-coupling reactions, where the iodo group reacts preferentially over the bromo group, enabling sequential functionalization. It also finds application as a flame retardant in polymer systems, where halogen release during combustion interrupts radical chain reactions, and as an antimicrobial and colorant intermediate in textile and leather processing.

This material is supplied as a crystalline powder or needles and is subject to REACH registration requirements within the European Economic Area. Procurement teams should confirm supplier SDS documentation and purity certificates prior to ordering, as grade specifications vary by intended application.