1-Deoxynojirimycin

1-Deoxynojirimycin (CAS 19130-96-2), also known as DNJ, Moranoline, Duvoglustat, and S-GI, is a naturally occurring iminosugar alkaloid originally isolated from mulberry plants. It carries no assigned E-code. Its molecular formula is C6H13NO4.

In personal care formulations, DNJ functions as a humectant and skin conditioner by mimicking glucose structures and interacting with glycosidase enzymes at the cellular level, supporting moisture retention and barrier integrity. It is also incorporated into hair care products as a conditioning agent that modifies surface interactions between the hair shaft and formulation matrix.

DNJ is supplied for pharmaceutical and cosmetic applications and is subject to REACH registration requirements within the EU. Procurement teams should confirm grade specifications, including purity levels appropriate for topical or investigational pharmaceutical use, with the supplier prior to ordering. Standard packaging formats vary by volume and application requirement.