SoleChem

2,2-dimethylbutanoyl chloride

CAS 5856-77-9
EC 227-478-5
Formula C6H11ClO
MW 134.6 g/mol
Pharmaceutical Intermediates Biotechnology & Life SciencesPersonal Care & CosmeticsPharmaceuticals & Healthcare Preservation & BiocideCatalysisFlavoring & Acidulant

Description

2,2-Dimethylbutanoyl chloride (CAS 5856-77-9, EC 227-478-5) is an acyl chloride supplied as a liquid under the synonyms 2,2-Dimethylbutyryl chloride and Dimethylbutyrylchloride. It carries no assigned E-code. It belongs to the acid chloride class of reactive acylating agents within the pharmaceutical intermediates category.

In pharmaceutical synthesis, it functions as an acylating agent, transferring its acyl group to amines or alcohols to build protected intermediates or active pharmaceutical ingredients. In personal care formulations, its antimicrobial activity derives from disruption of microbial cell membranes, supporting preservation systems. It also serves as a catalyst component and fragrance precursor in select specialty applications.

This material is supplied under REACH compliance and is available in standard laboratory and bulk packaging formats suited to industrial procurement. Buyers should confirm grade specifications and purity certificates directly with the supplier. It is classified under HS code 29159000 for customs and import documentation purposes.

Physical Properties

Melting Point -20 °C
Boiling Point 130.3-131.3 °C
Density 0.9787 g/cm³ @ Temp: 20 °C
Flash Point 29°C
Color Clear Colorless
Form Oil
Water Solubility Reacts with water. Soluble in chloroform and ethyl acetate.
Refractive Index 1.4240

Safety & Handling (Learn More)

Danger GHS02 GHS05
H
H226H290H314H318
P
P210P233P234P240P241P242P243P260P264P280P316P317P321P363P390P405P406P501P264+P265P304+P340P370+P378P403+P235P301+P330+P331P302+P361+P354P303+P361+P353P305+P354+P338

Trade & Regulatory

HS Code 29159000
Storage Class 11 - Combustible Solids
WGK (Germany) 3

Other Names

Dimethylbutyrylchloride2,2-dimethylbutyl chloride2,2-Dimethylbutyryl chloride2,2-DimethylbutyricacidchlorideButyryl Chloride, 2,2-Dimethyl-Butanoyl chloride, 2,2-dimethyl-2,2-Dimethylbutyric acid chloride

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