2,3,4-Trihydroxybenzaldehyde
CAS 2144-08-3
EC 218-404-2
Formula C7H6O4
MW 154.12 g/mol
Pharmaceutical Intermediates Personal Care & CosmeticsPharmaceuticals & HealthcareFood & Nutrition Preservation & BiocideAntioxidant & StabilizerUV Protection & Stabilization
Description
2,3,4-Trihydroxybenzaldehyde (CAS 2144-08-3, EC 218-404-2) is an aromatic aldehyde carrying three hydroxyl groups on the benzene ring, also known as Pyrogallolaldehyde or Pyrogallolcarboxaldehyde. It carries no assigned E-code and is referenced in research literature under the NSC 22595 designation.
In cosmetic and pharmaceutical formulations, the compound acts as a radical scavenger through its polyhydroxyl structure, neutralising reactive oxygen species to slow oxidative degradation of active ingredients. It is also evaluated as a UV-absorbing intermediate in sunscreen systems and as a preservative booster where phenolic activity inhibits microbial growth.
The material is supplied as a powder under REACH registration requirements applicable to EU buyers. It falls under HS code 29124990 for customs classification. Procurement teams should confirm grade specifications against internal quality standards, as no Ph.Eur. or FCC monograph currently governs this substance.
In cosmetic and pharmaceutical formulations, the compound acts as a radical scavenger through its polyhydroxyl structure, neutralising reactive oxygen species to slow oxidative degradation of active ingredients. It is also evaluated as a UV-absorbing intermediate in sunscreen systems and as a preservative booster where phenolic activity inhibits microbial growth.
The material is supplied as a powder under REACH registration requirements applicable to EU buyers. It falls under HS code 29124990 for customs classification. Procurement teams should confirm grade specifications against internal quality standards, as no Ph.Eur. or FCC monograph currently governs this substance.
Physical Properties
| Melting Point | 230 °C (decomp) |
| Boiling Point | 237.46°C (rough estimate) |
| Density | 1.3725 (rough estimate) |
| Appearance | light brown to beige-brown powder |
| Color | Light brown to beige-brown |
| Form | Powder |
| Water Solubility | 1.541g/L at 25℃ |
| Refractive Index | 1.6400 (estimate) |
| Log P | 1.25 |
Safety & Handling (Learn More)
Warning GHS07
H
H302H315H319H335H412
P
P261P264P270P271P273P280P319P321P330P405P501P264+P265P301+P317P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29124990 |
| WGK (Germany) | 2 |
Other Names
Pyrogallolaldehyde2,3,4-THBPyrogallolcarboxaldehyde2,3,4-TrihydroxybenzaldeydePYROGALLOL-4-CARBOXALDEHYDE3,4-Dihydroxysalicylaldehyde2,3,4-Trihydroxybenazldehyde
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Raw Materials
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