2-Chloronicotinic acid

2-Chloronicotinic acid (CAS 2942-59-8, EC 220-937-0) is a chlorinated pyridinecarboxylic acid derivative, also referenced as CNIS, NSC 378, and 3-carboxy-2-chloropyridine. It carries no assigned E-code and is classified under HS code 29333999 within the broader organic acids category.

In pharmaceutical synthesis, it serves as a key building block for active ingredients targeting antimicrobial pathways, where the electron-withdrawing chlorine atom directs selective nucleophilic substitution. In agricultural formulations, it functions as a catalyst and surface-modifying agent, improving active ingredient uptake across treated surfaces. Personal care and textile applications exploit its biocidal and flame-retardant activity through controlled reactivity at the ring nitrogen.

This material is supplied as a white to cream powder meeting REACH registration requirements for the European market. Procurement teams should confirm grade specifications against internal quality standards, as no Ph.Eur. or FCC monograph currently applies. Standard packaging formats follow supplier-specific configurations; bulk and laboratory quantities are available on request.