2-Pyrrolidinone
CAS 616-45-5
EC 210-483-1
Formula C4H7NO
MW 85.1 g/mol
Solvents Personal Care & CosmeticsElectronicsPrinting & PackagingPharmaceuticals & HealthcarePlastics & Polymers Humectant & MoisturizingSolvent & CarrierPolymerization InitiationUV Protection & Stabilization
Description
2-Pyrrolidinone (CAS 616-45-5) is a cyclic lactam solvent also known as Butyrolactam, Pyrrolidone, or 2-Pyrrolidon, with the molecular formula C4H7NO. It carries no assigned E-code and is registered under EC number 210-483-1. It is commercially available under various trade designations across solvent and specialty chemical catalogues.
In pharmaceutical formulations, 2-Pyrrolidinone acts as a penetration enhancer and solvent carrier, improving active ingredient absorption through skin barriers. In electronics manufacturing, it dissolves resins and flux residues due to its strong solvating power toward polar and non-polar compounds. Personal care formulators use it as a humectant and UV-absorbing skin conditioner in topical products.
This material is supplied in technical and pharmaceutical grades, with compliance documentation available for REACH registration. Packaging is offered in standard drum and IBC formats suited to industrial procurement volumes. Buyers should confirm grade-specific compliance with Ph.Eur. or FCC requirements depending on their application.
In pharmaceutical formulations, 2-Pyrrolidinone acts as a penetration enhancer and solvent carrier, improving active ingredient absorption through skin barriers. In electronics manufacturing, it dissolves resins and flux residues due to its strong solvating power toward polar and non-polar compounds. Personal care formulators use it as a humectant and UV-absorbing skin conditioner in topical products.
This material is supplied in technical and pharmaceutical grades, with compliance documentation available for REACH registration. Packaging is offered in standard drum and IBC formats suited to industrial procurement volumes. Buyers should confirm grade-specific compliance with Ph.Eur. or FCC requirements depending on their application.
Physical Properties
| Melting Point | 25.0 °C |
| Boiling Point | 76 °C @ Press: 0.2 Torr |
| Density | 1.116 g/cm³ @ Temp: 25 °C |
| Flash Point | >230 °F |
| Appearance | Clear colorless to pale yellow liquid or |
| Color | Clear colorless to pale yellow |
| Form | Liquid or Low Melting Mass |
| Water Solubility | miscible |
| Vapor Pressure | 0.04 hPa (20 °C) |
| Refractive Index | n 20/D 1.487(lit.) |
| pH | 9-11 (100g/l, H2O, 20℃) |
| Log P | -0.71 at 20℃ |
Safety & Handling (Learn More)
Danger GHS05 GHS07 GHS08
H
H315H318H319H335H360
P
P203P261P264P271P280P317P318P319P321P405P501P264+P265P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338P305+P354+P338
Trade & Regulatory
| HS Code | 29339980 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 1 |
Other Names
Pyrrolidin-2-OnePyrrolidon2-pyrrolidonePyrrolidoneBUTYROLACTAM2-PYRROLIDON
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