4-Chloro-2-(trifluoromethyl)aniline
CAS 445-03-4
EC 207-151-3
Formula C7H5ClF3N
MW 195.57 g/mol
Pigments & Colorants Textile, Leather & PaperPharmaceuticals & HealthcarePersonal Care & Cosmetics Preservation & Biocide
Description
4-Chloro-2-(trifluoromethyl)aniline (CAS 445-03-4) is a fluorinated aromatic amine supplied under trade designations including C.I. 37055, Fast Scarlet Salt VD, and Scarlet Salt Nvd. It carries no assigned E-code. The compound belongs to the halogenated amine class and is catalogued under HS code 29214300.
In textile and leather processing, it functions as a diazonium-forming intermediate, coupling with naphthol substrates on fiber to produce azo colorants with strong fastness properties. In antimicrobial formulations, the electron-withdrawing trifluoromethyl and chloro substituents enhance membrane-disrupting activity, making it applicable in preservation systems for personal care and pharmaceutical manufacturing.
This material is available as a clear yellow liquid suitable for direct use in synthesis or formulation workflows. Suppliers operating under REACH registration provide safety data documentation aligned with EU GHS requirements. Packaging is typically offered in drum quantities for industrial procurement.
In textile and leather processing, it functions as a diazonium-forming intermediate, coupling with naphthol substrates on fiber to produce azo colorants with strong fastness properties. In antimicrobial formulations, the electron-withdrawing trifluoromethyl and chloro substituents enhance membrane-disrupting activity, making it applicable in preservation systems for personal care and pharmaceutical manufacturing.
This material is available as a clear yellow liquid suitable for direct use in synthesis or formulation workflows. Suppliers operating under REACH registration provide safety data documentation aligned with EU GHS requirements. Packaging is typically offered in drum quantities for industrial procurement.
Physical Properties
| Melting Point | 8.8 °C |
| Boiling Point | 76-78 °C @ Press: 4-5 Torr |
| Density | 1.386 g/mL at 25 °C(lit.) |
| Flash Point | 203 °F |
| Appearance | Clear yellow liquid |
| Color | Colorless to Orange to Green |
| Form | clear liquid |
| Vapor Pressure | 48.5-1013hPa at 110.5-208.2℃ |
| Refractive Index | n 20/D 1.507(lit.) |
| pH | 7.4 at 20℃ and 995mg/L |
| Log P | 2.68 |
Safety & Handling (Learn More)
Warning GHS07 GHS08
H
H302H312H315H319H332H335H373
P
P260P261P264P270P271P280P317P319P321P330P405P501P264+P265P301+P317P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29214300 |
| UN Number | 2810 |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 2 |
Other Names
4-Chloro-alpha,alpha,alpha-trifluoro-o-toluidineC.I. 37055Scarlet Salt NvdTIMTEC-BB SBB000345Fast Scarlet VD SaltFast Scarlet Salt VDDiazo Fast Scarlet VDLABOTEST-BB LT02085311
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Raw Materials
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