4'-Hydroxyacetophenone
CAS 99-93-4
EC 202-802-8
Formula C8H8O2
MW 136.15 g/mol
Flavors & Fragrances Pharmaceuticals & HealthcarePersonal Care & CosmeticsPlastics & PolymersPrinting & PackagingFood & Nutrition Flavoring & AcidulantUV Protection & StabilizationAntioxidant & StabilizerPolymerization Initiation
Description
4'-Hydroxyacetophenone (CAS 99-93-4), also known commercially as Piceol, p-Acetylphenol, and 4-Acetylphenol, is a phenolic ketone classified as a pharmaceutical intermediate. It carries no assigned E-code and is registered under EC 202-802-8, with HS code 29145000 for customs classification across EU trade.
In UV-curable systems, it functions as a photoinitiator by absorbing UV radiation and generating reactive species that trigger polymer crosslinking. In personal care and food formulations, its phenolic hydroxyl group scavenges free radicals, providing antioxidant stabilization, while its mild acetophenone character contributes floral, hay-like notes as a fragrance or flavor component.
This material is supplied as a pharmaceutical-grade crystalline powder compliant with REACH registration requirements. Buyers should confirm suitability against Ph.Eur. or FCC monographs depending on the intended application. Standard packaging formats for European B2B supply typically include 25 kg fiber drums or multi-layer bags.
In UV-curable systems, it functions as a photoinitiator by absorbing UV radiation and generating reactive species that trigger polymer crosslinking. In personal care and food formulations, its phenolic hydroxyl group scavenges free radicals, providing antioxidant stabilization, while its mild acetophenone character contributes floral, hay-like notes as a fragrance or flavor component.
This material is supplied as a pharmaceutical-grade crystalline powder compliant with REACH registration requirements. Buyers should confirm suitability against Ph.Eur. or FCC monographs depending on the intended application. Standard packaging formats for European B2B supply typically include 25 kg fiber drums or multi-layer bags.
Physical Properties
| Melting Point | 109.5 °C |
| Boiling Point | 146-149 °C |
| Density | 1.278 g/cm³ @ Temp: 25 °C |
| Flash Point | 166 °C |
| Appearance | almost white to beige crystalline powder |
| Color | Almost white to beige |
| Odor | at 10.00 % in dipropylene glycol. mild sweet hawthorn balsam mimosa |
| Form | Crystalline Powder |
| Water Solubility | 10 g/L (22 ºC) |
| Vapor Pressure | 0.002Pa at 20℃ |
| Refractive Index | 1.5577 (estimate) |
| Log P | 1.35 at 25℃ |
Safety & Handling (Learn More)
Warning GHS07
H
H302H315H319H335H412
P
P261P264P270P271P273P280P319P321P330P405P501P264+P265P301+P317P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29145000 |
| Storage Class | 13 - Non Combustible Solids |
| WGK (Germany) | 3 |
Other Names
1-(4-hydroxyphenyl)ethanonePiceol4-Hydroxyacetophenone4-hydroxy acetophenoneACETYLPHENOL4-ACETOPHENOL4-ACETYLPHENOLp-Acetylphenol
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