4-Phenylpiperidine-4-carboxylic acid tosylate
CAS 83949-32-0
EC 281-391-7
Formula C12H15NO2.C7H8O3S
MW 377.45 g/mol
Pharmaceutical Intermediates Pharmaceuticals & Healthcare Catalysis
Description
4-Phenylpiperidine-4-carboxylic Acid Tosylate (CAS 83949-32-0, EC 281-391-7) is a piperidine-based salt formed from 4-phenylpiperidine-4-carboxylic acid and p-toluenesulfonic acid. It carries no assigned E-code or widely recognized trade abbreviation. The tosylate salt form improves handling stability and solubility compared to the free acid.
This compound serves primarily as a building block in pharmaceutical synthesis, where the piperidine-4-carboxylic acid core is incorporated into active pharmaceutical ingredient (API) scaffolds targeting central nervous system pathways. The tosylate counterion acts as a leaving group or stabilizing agent in catalytic coupling and condensation steps, enabling controlled reactivity during multi-step synthesis sequences.
Supplied as an off-white to slightly beige crystalline powder, this material is available in research and commercial quantities under REACH compliance for the European market. It is classified under HS code 29333990. Procurement teams should request a certificate of analysis confirming purity grade and residual solvent data prior to formulation use.
This compound serves primarily as a building block in pharmaceutical synthesis, where the piperidine-4-carboxylic acid core is incorporated into active pharmaceutical ingredient (API) scaffolds targeting central nervous system pathways. The tosylate counterion acts as a leaving group or stabilizing agent in catalytic coupling and condensation steps, enabling controlled reactivity during multi-step synthesis sequences.
Supplied as an off-white to slightly beige crystalline powder, this material is available in research and commercial quantities under REACH compliance for the European market. It is classified under HS code 29333990. Procurement teams should request a certificate of analysis confirming purity grade and residual solvent data prior to formulation use.
Physical Properties
| Melting Point | 225-229 °C |
| Appearance | off-white to slightly beige crystalline powder |
Trade & Regulatory
| HS Code | 29333990 |
Other Names
4-CARBOXY-4-PHENYLPIPERIDINE TOSYLATE4-Carboxy-4-phenylpiperidine p-toluenesulfonate4-CARBOXY-4-PHENYLPIPERIDINIUM P-TOLUENESULFONATE4-PHENYL-4-PIPERIDINE CARBOXYLIC ACID-4-TOLUESULFO4-Phenylpiperidine-4-carboxylic acid 4-toluenesulfonate4-Phenyl-4-piperidinecarboxylic acid p-toluenesulfonate4-Phenyl-4-piperidinecarboxylic acid p-toluene sulfonate4-PHENYL-4-PIPERIDINE CARBOXYLIC ACID 4-TOLUENE SULFONATE
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