SoleChem

5-Hydroxy-l-tryptophan

CAS 4350-09-8
EC 224-411-1
Formula C11H12N2O3
MW 220.22 g/mol
Amino Acids & Peptides Personal Care & CosmeticsPharmaceuticals & Healthcare Humectant & MoisturizingAntioxidant & Stabilizer

Description

5-Hydroxy-L-Tryptophan (CAS 4350-09-8) is a naturally occurring amino acid and direct biochemical precursor to serotonin, commercially known under trade names including Quietim, Tript-OH, Levothym, and Triptene, and abbreviated as L-5-HTP. It carries no assigned E-code and is classified within the amino acids and peptides category.

In personal care formulations, L-5-HTP functions as a skin and hair conditioner by supporting cellular moisture retention and acting as a humectant that draws water to the stratum corneum. Its antioxidant activity stems from the indole hydroxyl group, which scavenges free radicals and helps protect formulations and biological tissues from oxidative degradation.

This material is supplied as a solid powder compliant with REACH registration requirements and is available in pharmaceutical-grade specifications aligned with Ph.Eur. monograph standards. Procurement quantities range from laboratory-scale packaging to bulk formats. Buyers should confirm grade suitability against FCC or pharmacopoeial specifications for their target application. HS code: 29339990.

Physical Properties

Melting Point 273 °C (decomp)
Boiling Point 361.16°C (rough estimate)
Density 0.902 g/mL at 25 °C(lit.)
Flash Point 175 °F
Appearance white to pale grey powder
Color white
Form solid
Water Solubility Slightly soluble
Refractive Index n 20/D 1.4850(lit.)
Log P -0.140 (est)

Safety & Handling (Learn More)

Danger GHS06 GHS07
H
H301H315H319H335
P
P261P264P270P271P280P319P321P330P405P501P264+P265P301+P316P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338

Trade & Regulatory

HS Code 29339990
UN Number 2811
ADR Class 6.1
Packing Group III
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 3

Other Names

(2S)-2-amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acidLevothymTript-OHCincofarm5-HTPL-5-HTPQuietimTriptenePretonine

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