9-Borabicyclo[3.3.1]nonane

9-Borabicyclo[3.3.1]nonane, commonly known as 9-BBN (CAS 280-64-8, EC 206-000-9), is a selective organoborane reagent used as a hydroboration agent and catalyst precursor in synthetic chemistry. It is commercially available as a crystalline solid or as a 0.5 M solution in toluene.

In pharmaceutical synthesis, 9-BBN performs hydroboration of alkenes with high regioselectivity, delivering boron to the less hindered carbon to enable subsequent Suzuki-Miyaura cross-coupling reactions. This precision makes it a preferred reagent for constructing complex carbon frameworks in active pharmaceutical ingredient (API) manufacturing and biotechnology research.

9-BBN is supplied under REACH compliance and is classified under HS code 29319090. It is available in both neat crystalline form and as a toluene solution, with packaging options suited to laboratory and pilot-scale procurement. No E-code or food-grade designation applies to this substance.