Acetaminophen
CAS 103-90-2
EC 203-157-5
Formula C8H9NO2
MW 151.16 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & Cosmetics Antioxidant & StabilizerUV Protection & Stabilization
Description
Acetaminophen (CAS 103-90-2), also known as paracetamol, is a synthetic organic compound carrying no assigned E-code. It is commercially available under trade names including Amadil, Alvedon, and Acetagesic, and is classified within pharmaceutical intermediates under HS code 29242930.
In pharmaceutical manufacturing, acetaminophen serves as the active analgesic and antipyretic ingredient in finished dosage forms, functioning by inhibiting prostaglandin synthesis in the central nervous system. In personal care formulations, it acts as an antioxidant and UV stabilizer, intercepting free radicals and absorbing UV radiation to protect product integrity and skin.
Acetaminophen is supplied in pharmaceutical-grade crystalline powder form, conforming to Ph.Eur. and USP monograph specifications. It falls under REACH regulation and requires standard SDS documentation for EU trade. Procurement quantities typically range from kilogram laboratory packs to multi-tonne bulk consignments depending on application requirements.
In pharmaceutical manufacturing, acetaminophen serves as the active analgesic and antipyretic ingredient in finished dosage forms, functioning by inhibiting prostaglandin synthesis in the central nervous system. In personal care formulations, it acts as an antioxidant and UV stabilizer, intercepting free radicals and absorbing UV radiation to protect product integrity and skin.
Acetaminophen is supplied in pharmaceutical-grade crystalline powder form, conforming to Ph.Eur. and USP monograph specifications. It falls under REACH regulation and requires standard SDS documentation for EU trade. Procurement quantities typically range from kilogram laboratory packs to multi-tonne bulk consignments depending on application requirements.
Physical Properties
| Melting Point | 169-170.5 °C |
| Boiling Point | 500 °C |
| Density | 1.293 g/cm³ @ Temp: 21 °C |
| Flash Point | 11 °C |
| Appearance | White Solid |
| Color | White |
| Odor | odorless |
| Form | Crystals or Crystalline Powder |
| Water Solubility | 14 g/L (20 ºC) |
| Vapor Pressure | 0.008Pa at 25℃ |
| Refractive Index | 1.5810 (rough estimate) |
| pH | 5.5-6.5 (H2O, 20℃)(saturated solution) |
| Log P | 1.098 at 25℃ |
Safety & Handling (Learn More)
Warning GHS07 GHS09 GHS08
H
H302H315H319H335H341H370H371H372H373H401H411H412
P
P203P260P261P264P270P271P273P280P318P319P321P330P391P405P501P264+P265P301+P317P302+P352P304+P340P308+P316P332+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29242930 |
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| WGK (Germany) | 1 |
Other Names
ParacetamolN-(4-hydroxyphenyl)acetamideL484APAPAmadilAlvedonAcetagesic
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Raw Materials
Derivatives
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