Acetylcysteine
CAS 616-91-1
EC 210-498-3
Formula C5H9NO3S
MW 163.19 g/mol
Amino Acids & Peptides Pharmaceuticals & HealthcarePersonal Care & CosmeticsFood & Nutrition Humectant & MoisturizingAntioxidant & Stabilizer
Description
Acetylcysteine (CAS 616-91-1), also known as ACC or N-acetyl-L-cysteine, is a sulfur-containing amino acid derivative commercially available under trade names including Mucomyst, Fluimucil, and Airbron. It carries no assigned E-code and is classified under HS code 29309016 within pharmaceutical intermediates.
In pharmaceutical formulations, acetylcysteine acts as a mucolytic agent by cleaving disulfide bonds in mucus glycoproteins, reducing viscosity in respiratory preparations. In personal care, it functions as an antioxidant and humectant by donating free thiol groups that neutralize reactive oxygen species and support moisture retention in skin and hair formulations.
Acetylcysteine is supplied as a white crystalline powder in pharmaceutical and cosmetic grades, compliant with Ph.Eur. monograph standards and REACH regulations. It is available in quantities ranging from kilogram lots to bulk tonnage, with documentation packages suitable for EU market authorization submissions.
In pharmaceutical formulations, acetylcysteine acts as a mucolytic agent by cleaving disulfide bonds in mucus glycoproteins, reducing viscosity in respiratory preparations. In personal care, it functions as an antioxidant and humectant by donating free thiol groups that neutralize reactive oxygen species and support moisture retention in skin and hair formulations.
Acetylcysteine is supplied as a white crystalline powder in pharmaceutical and cosmetic grades, compliant with Ph.Eur. monograph standards and REACH regulations. It is available in quantities ranging from kilogram lots to bulk tonnage, with documentation packages suitable for EU market authorization submissions.
Physical Properties
| Melting Point | 109.5 °C |
| Boiling Point | 407.7±40.0 °C(Predicted) |
| Density | 1.249 (estimate) |
| Appearance | White crystalline powder |
| Color | White |
| Form | Solid |
| Water Solubility | Soluble in water, ethanol, methanol, dimethyl sulfoxide, hot isopropyl alcohol, methyl acetate and ethyl acetate. Insoluble in chloroform and ether. |
| Vapor Pressure | 0Pa at 20℃ |
| Refractive Index | 24 ° (C=JPC Method) |
| pH | 1.5-2.5 (20°C, 100g/L in H2O) |
| Log P | -0.6 at 23℃ |
Safety & Handling (Learn More)
Warning GHS07
H
H319
P
P280P264+P265P337+P317P305+P351+P338
Trade & Regulatory
| HS Code | 29309016 |
| WGK (Germany) | 3 |
Other Names
N-Acetyl-L-Cysteine(2R)-2-acetamido-3-sulfanylpropanoic acidNACL-acetylcysteineACCAirbronMucomyst
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