SoleChem

Acetylsalicylic acid

CAS 50-78-2
EC 200-064-1
Formula C9H8O4
MW 180.16 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & CosmeticsFood & Nutrition Preservation & BiocidepH Regulation & BufferingFlavoring & AcidulantAntioxidant & Stabilizer

Description

Acetylsalicylic acid (CAS 50-78-2) is a synthetic organic acid commonly known under trade names including Aspirin, Acetosal, and Rhodine. It carries no assigned E-code for food applications and is classified under HS code 29182200. The compound is produced by acetylation of salicylic acid and belongs to the broader category of organic acids.

In pharmaceutical formulations, acetylsalicylic acid functions as an active analgesic and anti-inflammatory agent by inhibiting cyclooxygenase enzymes. In personal care applications, it acts as a pH buffer and mild preservative, helping to stabilize emulsions and control microbial activity. At low concentrations it also serves as a skin-conditioning agent in topical preparations.

Acetylsalicylic acid is available in pharmaceutical grade meeting Ph.Eur. and USP specifications, supplied as a white crystalline powder. It is subject to REACH registration requirements within the EU. Standard packaging includes fiber drums and multi-layer bags, with documentation available to support GMP-compliant procurement processes.

Physical Properties

Melting Point 135 °C
Boiling Point 140 °C
Density 1.40 g/cm³
Flash Point 250 °C
Appearance Acetylsalicylic acid is a white crystalline solid with a slightly bitter taste. It is odorless but hydrolyzes in moist air to give an acetic acid odor
Color white
Form crystalline
Water Solubility 3.3 g/L (20 ºC)
Refractive Index 1.4500 (estimate)
Log P 1.190

Safety & Handling (Learn More)

Danger GHS07 GHS08
H
H302H315H316H319H334H335H360H370H371H372H373H412
P
P203P233P260P261P264P270P271P273P280P284P318P319P321P330P403P405P501P264+P265P301+P317P302+P352P304+P340P308+P316P332+P317P337+P317P342+P316P362+P364P403+P233P305+P351+P338

Trade & Regulatory

HS Code 29182200
UN Number 1851
Storage Class 11 - Combustible Solids
WGK (Germany) 1

Other Names

2-acetyloxybenzoic acidAspirinacetysalicylic acidASARhodineACETICYLAcetosal

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