Alpha-Arbutin
CAS 84380-01-8
EC 440-470-8
Formula C12H16O7
MW 273.259 g/mol
Pharmaceutical Intermediates Personal Care & Cosmetics Humectant & MoisturizingAntioxidant & Stabilizer
Description
Alpha-Arbutin (CAS 84380-01-8, EC 440-470-8, formula C12H16O7) is a glycosylated hydroquinone derivative used primarily in cosmetic and pharmaceutical formulations. It carries no assigned E-code. It is also referenced as α-Arbutin or Α-Arbutin in supplier and regulatory documentation.
In skin care formulations, Alpha-Arbutin functions as a tyrosinase inhibitor, reducing melanin synthesis to address hyperpigmentation and uneven skin tone. It also acts as a humectant, drawing and retaining moisture within the stratum corneum, and provides antioxidant protection by scavenging free radicals that contribute to oxidative skin stress.
Alpha-Arbutin is supplied as a solid and is subject to REACH registration requirements for EU market entry. Procurement teams should verify compliance with applicable cosmetic ingredient regulations, including INCI listing confirmation. Standard packaging formats vary by supplier; buyers should confirm grade specifications and certificate of analysis requirements at the point of inquiry.
In skin care formulations, Alpha-Arbutin functions as a tyrosinase inhibitor, reducing melanin synthesis to address hyperpigmentation and uneven skin tone. It also acts as a humectant, drawing and retaining moisture within the stratum corneum, and provides antioxidant protection by scavenging free radicals that contribute to oxidative skin stress.
Alpha-Arbutin is supplied as a solid and is subject to REACH registration requirements for EU market entry. Procurement teams should verify compliance with applicable cosmetic ingredient regulations, including INCI listing confirmation. Standard packaging formats vary by supplier; buyers should confirm grade specifications and certificate of analysis requirements at the point of inquiry.
Physical Properties
| Melting Point | 200-201 °C |
| Boiling Point | 561.6±50.0 °C(Predicted) |
| Density | 1.556±0.06 g/cm3(Predicted) |
| Color | White to Off-White |
| Form | Solid |
Safety & Handling (Learn More)
Warning GHS07
H
H302
P
P264P270P330P501P301+P317
Trade & Regulatory
| HS Code | 2938.90.0000 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
Α-ArbutinAlpha ArbutinHydroquinone O-α-D-glucopyranoside4-Hydroxyphenyl α-D-glucopyranosideα-D-Glucopyranoside, 4-hydroxyphenyl4-hydroquinone-alpha-d-glucopyranoside
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