(+/-)-Alpha-lipoic acid
CAS 1077-28-7
EC 214-071-2
Formula C8H14O2S2
MW 206.33 g/mol
Vitamins & Nutrients Food & NutritionPharmaceuticals & HealthcarePersonal Care & Cosmetics Antioxidant & StabilizerFlavoring & AcidulantCatalysisPreservation & Biocide
Description
(+/-)-Alpha-Lipoic Acid (CAS 1077-28-7), also known as thioctic acid or liponic acid and abbreviated ALA, is a naturally occurring organosulfur compound produced as a racemic mixture of its R and S enantiomers. It carries no assigned E-code and is classified under HS code 29349900.
In pharmaceutical and nutraceutical formulations, ALA functions as a redox-active antioxidant by cycling between oxidised and reduced states, regenerating co-antioxidants such as vitamins C and E. In food processing, it acts as a preservative and heat stabiliser by chelating pro-oxidant metal ions, slowing lipid oxidation during thermal treatment.
ALA is supplied as a light-yellow crystalline powder in pharmaceutical-grade (Ph.Eur.) and food-grade (FCC) specifications, with REACH compliance documentation available. Standard packaging includes 25 kg fibre drums, with smaller quantities available on request.
In pharmaceutical and nutraceutical formulations, ALA functions as a redox-active antioxidant by cycling between oxidised and reduced states, regenerating co-antioxidants such as vitamins C and E. In food processing, it acts as a preservative and heat stabiliser by chelating pro-oxidant metal ions, slowing lipid oxidation during thermal treatment.
ALA is supplied as a light-yellow crystalline powder in pharmaceutical-grade (Ph.Eur.) and food-grade (FCC) specifications, with REACH compliance documentation available. Standard packaging includes 25 kg fibre drums, with smaller quantities available on request.
Physical Properties
| Melting Point | 60-61 °C |
| Boiling Point | 160-165 °C |
| Density | 1.2888 (rough estimate) |
| Flash Point | 160-165°C |
| Appearance | Light-Yellow Solid |
| Color | Yellow |
| Form | Crystals or Crystalline Powder |
| Water Solubility | 0.9 g/L (20 ºC) |
| Refractive Index | 1.5200 (estimate) |
| Log P | 2.530 (est) |
Safety & Handling (Learn More)
Warning GHS07 GHS09
H
H302H315H317H319H335H411H412
P
P261P264P270P271P272P273P280P319P321P330P391P405P501P264+P265P301+P317P302+P352P304+P340P332+P317P333+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29349900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
Lipoic AcidThioctic acidalpha-Lipoic acidalpha Lipoic acid5-(dithiolan-3-yl)pentanoic acidliponic acid(RS)-thioctic acid
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