Ascorbyl palmitate
CAS 137-66-6
EC 205-305-4
Formula C22H38O7
MW 414.53 g/mol
Vitamins & Nutrients Personal Care & CosmeticsFood & NutritionPharmaceuticals & Healthcare Emulsification & DispersionAntioxidant & StabilizerHumectant & MoisturizingLubrication
Description
Ascorbyl Palmitate (CAS 137-66-6, E304i) is a fat-soluble ester formed by combining ascorbic acid with palmitic acid. It is also referred to as L-Ascorbyl Palmitate, Ascorbyl Monopalmitate, and Ascorbic Palmitate, and carries the EC number 205-305-4 with molecular formula C22H38O7.
In food manufacturing, it functions as a lipid-phase antioxidant, scavenging free radicals in oils and fats to delay rancidity without affecting flavour profiles. In cosmetic formulations, it acts simultaneously as an emulsifier and emollient, stabilising oil-in-water systems while supporting skin barrier function. Pharmaceutical manufacturers use it as a heat stabiliser and lubricating agent in lipid-based delivery systems.
Ascorbyl Palmitate is available in food-grade (FCC), cosmetic-grade, and pharmaceutical-grade (Ph.Eur.) specifications. It is approved under EU regulation as E304i and is subject to REACH registration. Typical packaging includes fibre drums and multi-layer bags; HS code 29362700 applies for import classification.
In food manufacturing, it functions as a lipid-phase antioxidant, scavenging free radicals in oils and fats to delay rancidity without affecting flavour profiles. In cosmetic formulations, it acts simultaneously as an emulsifier and emollient, stabilising oil-in-water systems while supporting skin barrier function. Pharmaceutical manufacturers use it as a heat stabiliser and lubricating agent in lipid-based delivery systems.
Ascorbyl Palmitate is available in food-grade (FCC), cosmetic-grade, and pharmaceutical-grade (Ph.Eur.) specifications. It is approved under EU regulation as E304i and is subject to REACH registration. Typical packaging includes fibre drums and multi-layer bags; HS code 29362700 applies for import classification.
Physical Properties
| Melting Point | 116 °C |
| Boiling Point | 512.7±50.0 °C(Predicted) |
| Density | 1.150±0.06 g/cm3(Predicted) |
| Color | White to Pale Gray |
| Odor | wh. or yel.-wh. powd., citrus odor |
| Form | neat |
| Refractive Index | 22.5 ° (C=1, EtOH) |
| Log P | 6.5 at 30℃ and pH1.9 |
Safety & Handling (Learn More)
Warning GHS07
H
H319H412
P
P273P280P501P264+P265P337+P317P305+P351+P338
Trade & Regulatory
| HS Code | 29362700 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 1 |
Other Names
E304i6-O-palmitoylascorbic acidL-ascorbic acid 6-hexadecanoateAscorbic palmitateL-Ascorbyl palmitateAscorbylpalmitic acidAscorbyl monopalmitate
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