Benzenesulfonyl chloride

Benzenesulfonyl chloride (CAS 98-09-9, EC 202-636-6) is an organosulfur reagent also known as phenylsulfonyl chloride, benzene sulfochloride, and NSC 2864. It carries no assigned E-code and is classified under HS code 29049090 within the pharmaceutical intermediates category.

In pharmaceutical synthesis, benzenesulfonyl chloride acts as a sulfonylating agent, introducing the phenylsulfonyl group onto amines and alcohols to produce protected intermediates or active sulfonamide compounds. In water treatment and textile processing, it functions as a biocidal precursor, where its reactive sulfonyl chloride group disrupts microbial cell function through electrophilic attack on biological nucleophiles.

This material is supplied as a liquid-phase reagent and is subject to REACH registration requirements for European procurement. Buyers should confirm supplier compliance documentation, SDS availability, and packaging specifications prior to ordering, as handling requirements reflect its reactive and corrosive classification.