Benzonitrile

Benzonitrile (CAS 100-47-0, EC 202-855-7), also known as cyanobenzene or phenyl cyanide, is an aromatic nitrile compound with the molecular formula C7H5N. It carries no assigned E-code and is classified under HS code 29269090. It is commercially recognised under synonyms including Benzonitril and Phenyl Cyanide.

In pharmaceutical synthesis, benzonitrile serves as a ligand and solvent in palladium-catalysed cross-coupling reactions, coordinating to the metal centre to stabilise reactive intermediates. It also functions as an antimicrobial and antioxidant agent in personal care formulations, where its nitrile group contributes to inhibiting oxidative degradation and microbial growth.

Benzonitrile is supplied as a reagent-grade liquid meeting REACH compliance requirements for the European market. Standard packaging formats include drums and intermediate bulk containers. Buyers should confirm purity specifications against applicable pharmacopoeial or internal quality standards prior to procurement.