Benzoyl chloride
CAS 98-88-4
EC 202-710-8
Formula C7H5ClO
MW 140.57 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcareBiotechnology & Life SciencesPersonal Care & Cosmetics Preservation & BiocideCatalysis
Description
Benzoyl chloride (CAS 98-88-4, EC 202-710-8, formula C7H5ClO) is an acyl chloride derived from benzoic acid, also referenced under the names Benzoic acid chloride, chlorure de benzoyle, and the trade code B 0105. It carries no assigned E-code and is classified as a pharmaceutical intermediate.
In pharmaceutical synthesis, benzoyl chloride acts as an acylating agent, transferring its benzoyl group to amines, alcohols, and other nucleophiles to form stable benzoate esters and benzamides used in active ingredient production. In personal care formulations, it functions as an antimicrobial precursor and catalyst in reactions that generate preservative compounds or condition skin-active molecules.
This material is supplied as a liquid-phase reagent compliant with REACH registration requirements applicable to EU-market distribution. Procurement teams should confirm purity grade specifications against pharmaceutical or technical standards relevant to their application. HS code 29310095 applies for import and export classification within European trade documentation.
In pharmaceutical synthesis, benzoyl chloride acts as an acylating agent, transferring its benzoyl group to amines, alcohols, and other nucleophiles to form stable benzoate esters and benzamides used in active ingredient production. In personal care formulations, it functions as an antimicrobial precursor and catalyst in reactions that generate preservative compounds or condition skin-active molecules.
This material is supplied as a liquid-phase reagent compliant with REACH registration requirements applicable to EU-market distribution. Procurement teams should confirm purity grade specifications against pharmaceutical or technical standards relevant to their application. HS code 29310095 applies for import and export classification within European trade documentation.
Physical Properties
| Melting Point | -1.0 °C |
| Boiling Point | 197.2 °C @ Press: 760 Torr |
| Density | 1.2070 g/cm³ @ Temp: 25 °C |
| Flash Point | 156 °F |
| Appearance | Benzoyl chloride is a colorless to slight brown liquid with a strong, penetrating odor. |
| Color | Clear |
| Odor | Pungent characteristic. |
| Form | Liquid |
| Water Solubility | reacts |
| Vapor Pressure | 1 mm Hg ( 32 °C) |
| Refractive Index | n 20/D 1.553(lit.) |
| pH | 2 (1g/l, H2O, 20℃) |
| Log P | 1.44 at 21℃ and pH6 |
Safety & Handling (Learn More)
Danger GHS05 GHS07 GHS06 GHS08 GHS09
H
H227H302H311H312H314H317H318H330H331H332H351H371H372H400H402H410
P
P203P210P260P261P262P264P270P271P272P273P280P284P316P317P318P319P320P321P330P363P391P403P405P501P264+P265P301+P317P302+P352P304+P340P308+P316P333+P317P361+P364P362+P364P370+P378P403+P233P301+P330+P331P302+P361+P354P305+P354+P338
Trade & Regulatory
| HS Code | 29310095 |
| UN Number | 1736 |
| ADR Class | 8 |
| Packing Group | II |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 1 |
Other Names
B 0105Benzoylchloridechloruredebenzoyle-ChlorobenzaldehydeBENZOIC ACID CHLORIDELABOTEST-BB LTBB000456
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Raw Materials
Derivatives
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