Capsaicin
CAS 404-86-4
EC 206-969-8
Formula C18H27NO3
MW 305.41 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & Cosmetics Antioxidant & Stabilizer
Description
Capsaicin (CAS 404-86-4) is the active pungent compound found naturally in chili peppers of the Capsicum genus. It is commercially available under trade names including Zostrix, Capsin P 50, and Ratden PE 40, and carries no assigned E-code. It is classified as a pharmaceutical intermediate with the molecular formula C18H27NO3.
In pharmaceutical topical formulations, capsaicin depletes substance P from peripheral sensory neurons, reducing pain signal transmission and making it a functional active in analgesic creams and patches. In personal care, it is incorporated into scalp and circulation-stimulating products where its vasodilatory action drives the intended effect.
Capsaicin is sourced in pharmaceutical-grade form aligned with Ph.Eur. monograph standards and is subject to REACH registration requirements for EU supply. It is handled under controlled conditions given its potency, and supplied in sealed quantities appropriate for laboratory and small-batch production use. Buyers should confirm purity specification and documentation requirements at point of inquiry.
In pharmaceutical topical formulations, capsaicin depletes substance P from peripheral sensory neurons, reducing pain signal transmission and making it a functional active in analgesic creams and patches. In personal care, it is incorporated into scalp and circulation-stimulating products where its vasodilatory action drives the intended effect.
Capsaicin is sourced in pharmaceutical-grade form aligned with Ph.Eur. monograph standards and is subject to REACH registration requirements for EU supply. It is handled under controlled conditions given its potency, and supplied in sealed quantities appropriate for laboratory and small-batch production use. Buyers should confirm purity specification and documentation requirements at point of inquiry.
Physical Properties
| Melting Point | 65 °C |
| Boiling Point | 210-220 °C @ Press: 0.01 Torr |
| Density | 1.1037 (rough estimate) |
| Flash Point | 113 °C |
| Appearance | Crystalline solid, rectangular plates, or scales. Pungent odor and burning taste. |
| Color | Off-white |
| Odor | mild warm herbal |
| Form | Off-white solid |
| Water Solubility | insoluble |
| Refractive Index | 1.5100 (estimate) |
| Log P | 4.00 |
Trade & Regulatory
| HS Code | 29339900 |
| UN Number | 2811 |
| ADR Class | 6.1 |
| Packing Group | II |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
| WGK (Germany) | 3 |
Other Names
ZostrixCapsaicineCapsin P 50Ratden PE 40(E)-CAPSAICINCAPSAICIN, NATURAL8-METHYL-N-VANILLYL-6-NONENAMIDE
Related Products
Raw Materials
Need a chemical? Get a quote within 24 hours.