Celecoxib
CAS 169590-42-5
EC 685-962-5
Formula C17H14F3N3O2S
MW 381.37 g/mol
Pharmaceutical Intermediates Pharmaceuticals & Healthcare Preservation & BiocideFoam Control
Description
Celecoxib (CAS 169590-42-5, EC 685-962-5) is a pharmaceutical-grade sulfonamide compound known under trade names including Celebrex, Celebra, and Xilebao, as well as research designations YM 177 and Celecox. It carries no assigned E-code and is classified under HS code 29350090 within the pharmaceutical intermediates category.
In pharmaceutical manufacturing, celecoxib functions as a selective COX-2 inhibitor and serves as an active intermediate in anti-inflammatory drug synthesis. Its sulfonamide structure also contributes foam-control properties in specific process formulations, and its antimicrobial activity supports preservation functions in certain pharmaceutical preparation workflows.
Celecoxib is supplied as a white to pale yellow powder meeting pharmaceutical-grade specifications aligned with Ph.Eur. and REACH compliance requirements. Procurement teams should confirm applicable grade documentation, certificate of analysis, and GMP status with the supplier prior to ordering, as regulatory requirements vary by end application and jurisdiction.
In pharmaceutical manufacturing, celecoxib functions as a selective COX-2 inhibitor and serves as an active intermediate in anti-inflammatory drug synthesis. Its sulfonamide structure also contributes foam-control properties in specific process formulations, and its antimicrobial activity supports preservation functions in certain pharmaceutical preparation workflows.
Celecoxib is supplied as a white to pale yellow powder meeting pharmaceutical-grade specifications aligned with Ph.Eur. and REACH compliance requirements. Procurement teams should confirm applicable grade documentation, certificate of analysis, and GMP status with the supplier prior to ordering, as regulatory requirements vary by end application and jurisdiction.
Physical Properties
| Melting Point | 157-159 °C |
| Boiling Point | 529.0±60.0 °C(Predicted) |
| Density | 1.549 g/cm³ (solid) |
| Appearance | White to Pale Yellow Solid |
| Color | white to off-white |
| Form | powder |
| Water Solubility | 7mg/L(25 ºC) |
Safety & Handling (Learn More)
Danger GHS07 GHS08 GHS09
H
H317H319H360H401H411
P
P203P261P272P273P280P318P321P391P405P501P264+P265P302+P352P333+P317P337+P317P362+P364P305+P351+P338
Trade & Regulatory
| HS Code | 29350090 |
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| WGK (Germany) | 3 |
Other Names
Celecox®Onsenal®YM 177CelecoxCelebraXilebaoSC 58635CELEBREX
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