Chapso

CHAPSO (CAS 82473-24-3) is a zwitterionic detergent derived from cholic acid, belonging to the CHAPS-family of bile acid-based surfactants. It is commercially available under designations including CHAPSO SigmaUltra and CHAPSO Electrophoresis Grade. No E-code applies to this substance.

In membrane protein research, CHAPSO solubilises lipid bilayers while preserving native protein conformation, making it suitable for receptor isolation and functional assays. In electrophoresis applications, it maintains protein activity during gel separation by preventing irreversible aggregation. Its zwitterionic character allows effective dispersion at physiological pH without introducing net charge to the system.

CHAPSO is supplied as a white crystalline powder in analytical and electrophoresis-grade specifications. It falls under REACH regulation (EC 617-338-5) and is classified under HS code 2924297099 for customs purposes. Packaging formats typically range from small laboratory quantities to bulk orders for pharmaceutical and biotechnology procurement.