Chlorhexidine digluconate

Chlorhexidine digluconate (CAS 18472-51-0) is a broad-spectrum antimicrobial agent commercially known under trade names including Hibiclens, Peridex, and Abacil. It carries no E-code designation and is classified under HS code 29252900. The compound is commonly abbreviated as CHG or chlorhexidine gluconate in formulation and procurement contexts.

In pharmaceutical and personal care applications, CHG disrupts bacterial cell membranes by binding to negatively charged phospholipids, causing cytoplasmic leakage and cell death. It is used as the active biocide in surgical scrubs, wound antiseptics, and oral rinses, and functions as a skin protectant and conditioner in topical formulations at concentrations typically between 0.05% and 4%.

Chlorhexidine digluconate is supplied as an aqueous solution and is available in pharmaceutical grades compliant with Ph.Eur. and USP monographs. It falls under REACH registration requirements for EU supply. Standard commercial concentrations are 20% w/v solution, with packaging in drums and IBCs for bulk procurement.