SoleChem

Chlorphenesin

CAS 104-29-0
EC 203-192-6
Formula C9H11ClO3
MW 202.63 g/mol
Pharmaceutical Intermediates Personal Care & CosmeticsPharmaceuticals & Healthcare Preservation & Biocide

Description

Chlorphenesin (CAS 104-29-0) is a chlorinated glycerol ether active used as an antimicrobial and skin conditioner in cosmetic and pharmaceutical formulations. It is sold under trade names including Mycil and Adermykon, and also referenced as Clorfenesina in Spanish-language regulatory documentation. It carries no assigned E-code.

In personal care formulations, chlorphenesin functions by disrupting microbial cell membrane integrity, providing broad-spectrum activity against bacteria and fungi at low use concentrations. It is commonly incorporated into leave-on and rinse-off cosmetics as a preservative booster, often paired with other actives to extend the preservation system. In pharmaceutical topical preparations, it serves as an antifungal active ingredient.

Chlorphenesin is supplied as a solid and is subject to REACH registration requirements within the EU. Procurement teams should verify compliance with Cosmetics Regulation (EC) No 1223/2009, which restricts its use to a maximum of 0.3% in finished cosmetic products. Standard industrial packaging formats apply; contact our team for available lot sizes.

Physical Properties

Melting Point 78 °C
Boiling Point 290.96°C (rough estimate)
Density 1.2411 (rough estimate)
Color White to Off-White
Form Solid
Water Solubility Slightly soluble in water.
Vapor Pressure 0Pa at 25℃
Refractive Index 1.5470 (estimate)
Log P 1.23 at 23℃

Safety & Handling (Learn More)

Danger GHS05 GHS07
H
H302H315H318H319H332H335
P
P261P264P270P271P280P317P319P321P330P405P501P264+P265P301+P317P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338P305+P354+P338

Trade & Regulatory

HS Code 29094990

Other Names

Chlorphenesin Carbamate3-(4-chlorophenoxy)propane-1,2-diolClorfenesinaChlorphenesineMYCILAdermykon

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