Cooling agent WS-23
CAS 51115-67-4
EC 256-974-4
Formula C10H21NO
MW 171.28 g/mol
Flavors & Fragrances Personal Care & CosmeticsFood & Nutrition Flavoring & AcidulantAntioxidant & StabilizerCatalysis
Description
Cooling Agent WS-23 (CAS 51115-67-4, FEMA 3804) is a synthetic cooling sensate belonging to the carboxamide family. It produces a pronounced cooling sensation without minty or menthol-associated taste, making it chemically distinct from menthol-based alternatives. It carries no E-code designation.
In oral care and food formulations, WS-23 activates TRPM8 cold receptors in sensory tissue, delivering a clean, sustained cooling effect at concentrations typically between 0.01% and 0.1%. In personal care products such as after-sun gels and skin tonics, it functions as a cooling sensate and skin conditioner, enhancing perceived freshness without altering fragrance profiles.
WS-23 is supplied as a white crystalline solid and is available in food-grade quality aligned with FCC specifications and FEMA GRAS status. It falls under HS code 29242990 and is subject to REACH registration requirements within the EU. Standard packaging includes kilogram quantities suitable for laboratory and production-scale procurement.
In oral care and food formulations, WS-23 activates TRPM8 cold receptors in sensory tissue, delivering a clean, sustained cooling effect at concentrations typically between 0.01% and 0.1%. In personal care products such as after-sun gels and skin tonics, it functions as a cooling sensate and skin conditioner, enhancing perceived freshness without altering fragrance profiles.
WS-23 is supplied as a white crystalline solid and is available in food-grade quality aligned with FCC specifications and FEMA GRAS status. It falls under HS code 29242990 and is subject to REACH registration requirements within the EU. Standard packaging includes kilogram quantities suitable for laboratory and production-scale procurement.
Physical Properties
| Melting Point | 60 °C |
| Boiling Point | 84 °C |
| Density | 0.9419 (rough estimate) |
| Color | White to Almost white |
| Odor | at 25.00 % in dipropylene glycol. mild cooling mentholic minty |
| Form | Solid |
| Vapor Pressure | 0.3-0.32Pa at 25℃ |
| Refractive Index | 1.4621 (estimate) |
| Log P | 2.5 at 25℃ and pH7 |
Safety & Handling (Learn More)
Warning GHS07
H
H302
P
P264P270P330P501P301+P317
Trade & Regulatory
| HS Code | 29242990 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
N,2,3-Trimethyl-2-Propan-2-Ylbutanamidemethyl diisopropyl propionamideWS 23WS-23Cooling Sensate WS 23WS 23 (cooling agent)methyldiisopropylpropionamideN,2,3-Trimethyl-2-isopropylbutamide
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