D-Mannitol
CAS 69-65-8
EC 200-711-8
Formula C6H14O6
MW 182.17 g/mol
Sweeteners & Food Additives Pharmaceuticals & HealthcarePersonal Care & CosmeticsFood & Nutrition Humectant & MoisturizingChelation & Sequestration
Description
D-Mannitol (CAS 69-65-8), also known as Mannite and approved as food additive E421, is a naturally occurring sugar alcohol found in plants and fungi. It carries the EC number 200-711-8 and molecular formula C6H14O6, and is commercially produced through hydrogenation of fructose or mannose.
In pharmaceutical tablet manufacturing, D-Mannitol functions as a direct-compression excipient and diluent, providing a cool mouthfeel and low hygroscopicity that protects moisture-sensitive active ingredients. In personal care formulations, it acts as a humectant by binding water molecules within the skin matrix, and as a chelator that sequesters metal ions to stabilise product systems.
D-Mannitol is available in pharmaceutical grade (Ph.Eur., USP/NF), food grade (FCC, E421), and cosmetic grade forms. It is supplied as a crystalline powder under REACH compliance and is typically offered in 25 kg bags or bulk quantities. Relevant HS code for import classification is 2905.43.00.
In pharmaceutical tablet manufacturing, D-Mannitol functions as a direct-compression excipient and diluent, providing a cool mouthfeel and low hygroscopicity that protects moisture-sensitive active ingredients. In personal care formulations, it acts as a humectant by binding water molecules within the skin matrix, and as a chelator that sequesters metal ions to stabilise product systems.
D-Mannitol is available in pharmaceutical grade (Ph.Eur., USP/NF), food grade (FCC, E421), and cosmetic grade forms. It is supplied as a crystalline powder under REACH compliance and is typically offered in 25 kg bags or bulk quantities. Relevant HS code for import classification is 2905.43.00.
Physical Properties
| Melting Point | 166-168 °C |
| Boiling Point | 290-295 °C @ Press: 3.5 Torr |
| Density | 1.52 g/cm³ @ Temp: 20 °C |
| Flash Point | 290-295°C/3.5mm |
| Appearance | White crystalline powder |
| Color | White |
| Odor | at 100.00 %. odorless |
| Form | Crystalline Powder |
| Water Solubility | soluble |
| Refractive Index | 1.3330 (estimate) |
| pH | 5.0-6.5 (25℃, 1M in H2O) |
| Log P | -3.262 (est) |
Trade & Regulatory
| HS Code | 29054300 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 2 |
Other Names
(2R,3R,4R,5R)-hexane-1,2,3,4,5,6-hexole421e-421e 421D-(-)-MannitolManniteDiosmolMannidex
Related Products
Raw Materials
Need a chemical? Get a quote within 24 hours.