SoleChem

d-Panthenol

CAS 81-13-0
EC 201-327-3
Formula C9H19NO4
MW 205.25 g/mol
Vitamins & Nutrients Personal Care & CosmeticsPharmaceuticals & Healthcare Humectant & MoisturizingAntioxidant & StabilizerCross-linking & Curing

Description

D-Panthenol (CAS 81-13-0) is the biologically active dextrorotatory form of pantothenic acid (vitamin B5), commercially known under trade names such as Bepanthen, Bepantol, Bepanthene, and Cozyme. It carries no assigned E-code and is identified under EC number 201-327-3 with molecular formula C9H19NO4.

In personal care formulations, D-Panthenol functions as a humectant by binding water within the hair cortex and skin layers, improving elasticity and reducing breakage in conditioning products. In pharmaceutical topical preparations, it converts enzymatically to pantothenic acid within skin tissue, supporting epithelial repair. It also serves as a crosslinker and heat stabilizer in select polymer and coating applications.

D-Panthenol is available in cosmetic and pharmaceutical grades, compliant with Ph.Eur. monograph standards and REACH registration requirements. It is supplied as a viscous liquid in drums and IBCs. Procurement professionals should confirm grade specification against intended application, as cosmetic and pharma grades carry distinct purity thresholds.

Physical Properties

Melting Point <25 °C
Boiling Point 118-120 °C @ Press: 0.02 Torr
Density 1.2 g/cm³ @ Temp: 20 °C
Flash Point 118-120°C/0.02m
Appearance clear colorless to slightly yellow viscous liquid
Color Clear colorless to slightly yellow
Form Viscous Liquid or Semi Solid
Water Solubility soluble
Vapor Pressure 0Pa at 25℃
Refractive Index 1.495-1.502
pH pH (100g/l,25℃) : 8.5~10.5
Log P -1.06 at 22℃

Trade & Regulatory

HS Code 29241990
Storage Class 10 - Combustible liquids
WGK (Germany) 1

Other Names

DexpanthenolD-pantothenol(+)-panthenolCozymeBepantolPanthenolBepanthen

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