Diazolidinyl urea
CAS 78491-02-8
EC 278-928-2
Formula C8H14N4O7
MW 130.15 g/mol
Heterocyclic Compounds Personal Care & CosmeticsPharmaceuticals & Healthcare Preservation & BiocideHumectant & Moisturizing
Description
Diazolidinyl Urea (CAS 78491-02-8) is a formaldehyde-releasing antimicrobial preservative commonly known by the trade names Germall II and Germaben II-E. It carries no assigned E-code and is classified under heterocyclic compounds with the molecular formula C8H14N4O7.
In personal care formulations such as lotions, shampoos, and wet wipes, it inhibits bacterial and fungal growth by releasing controlled amounts of formaldehyde that disrupt microbial cell function. In pharmaceutical topical preparations, it serves a dual role as both a preservative and a humectant, helping to retain moisture in the product matrix.
Supplied as a white powder conforming to REACH registration requirements, this material is available in standard industrial packaging for B2B procurement. Buyers should verify compliance with EU Cosmetics Regulation Annex V restrictions on formaldehyde-releasing preservatives, including applicable concentration limits and mandatory labelling obligations.
In personal care formulations such as lotions, shampoos, and wet wipes, it inhibits bacterial and fungal growth by releasing controlled amounts of formaldehyde that disrupt microbial cell function. In pharmaceutical topical preparations, it serves a dual role as both a preservative and a humectant, helping to retain moisture in the product matrix.
Supplied as a white powder conforming to REACH registration requirements, this material is available in standard industrial packaging for B2B procurement. Buyers should verify compliance with EU Cosmetics Regulation Annex V restrictions on formaldehyde-releasing preservatives, including applicable concentration limits and mandatory labelling obligations.
Physical Properties
| Boiling Point | 421.04°C (rough estimate) |
| Density | 1.4734 (rough estimate) |
| Appearance | white powder |
| Color | White to Off-White |
| Form | Solid |
| Water Solubility | 1000g/L at 20℃ |
| Vapor Pressure | 0Pa at 20℃ |
| Refractive Index | 1.6590 (estimate) |
| Log P | 0.9 at 20℃ |
Safety & Handling (Learn More)
Warning GHS07
H
H315H317H319H412
P
P261P264P272P273P280P321P501P264+P265P302+P352P332+P317P333+P317P337+P317P362+P364P305+P351+P338
Trade & Regulatory
| HS Code | 29339900 |
| WGK (Germany) | 2 |
Other Names
N,N'-Bis(hydroxymethyl) ureahyl)-germall11Germall IIGermaben II-Eroxymethyl)ureaDiazolidinylureaDiszolidinylUrea
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