Diethylpropargylamine
CAS 4079-68-9
EC 223-804-5
Formula C7H13N
MW 111.18 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcareAgriculture & FeedBiotechnology & Life Sciences Polymerization InitiationCatalysis
Description
Diethylpropargylamine (CAS 4079-68-9, EC 223-804-5) is a tertiary amine bearing a terminal alkyne group, supplied as a clear liquid under synonyms including 3-(Diethylamino)propyne and 1-Diethylaminopropyne-2. It carries no assigned E-code and is classified under HS code 29221990 within the amines category.
In pharmaceutical and agrochemical synthesis, the terminal alkyne group participates in copper-catalysed azide-alkyne cycloaddition reactions, enabling selective conjugation steps in active ingredient construction. The diethylamino moiety also serves as a base catalyst and polymerisation initiator in speciality polymer systems, activating chain growth under controlled conditions.
Diethylpropargylamine is available for supply to European buyers in compliance with REACH registration requirements. It is offered in standard laboratory and bulk packaging formats suited to research-scale and industrial procurement. Buyers should confirm grade specifications and documentation requirements, including SDS and CoA, at point of order.
In pharmaceutical and agrochemical synthesis, the terminal alkyne group participates in copper-catalysed azide-alkyne cycloaddition reactions, enabling selective conjugation steps in active ingredient construction. The diethylamino moiety also serves as a base catalyst and polymerisation initiator in speciality polymer systems, activating chain growth under controlled conditions.
Diethylpropargylamine is available for supply to European buyers in compliance with REACH registration requirements. It is offered in standard laboratory and bulk packaging formats suited to research-scale and industrial procurement. Buyers should confirm grade specifications and documentation requirements, including SDS and CoA, at point of order.
Physical Properties
| Melting Point | 157-161°C |
| Boiling Point | 120-121 °C |
| Density | 0.8042 g/cm³ @ Temp: 25 °C |
| Flash Point | 156°C |
| Color | Colorless to Light orange to Yellow |
| Form | clear liquid |
| Water Solubility | Soluble in acid. Insoluble in water. |
| Vapor Pressure | 14.6hPa at 20℃ |
| Refractive Index | n 20/D 1.434 |
| Log P | 1.5 at 23℃ |
Safety & Handling (Learn More)
Danger GHS02 GHS05 GHS06 GHS07
H
H225H226H302H311H314H315H318H319H331H412
P
P210P233P240P241P242P243P260P261P262P264P270P271P273P280P316P317P321P330P363P405P501P264+P265P301+P317P302+P352P304+P340P332+P317P337+P317P361+P364P362+P364P370+P378P403+P233P403+P235P301+P330+P331P302+P361+P354P303+P361+P353P305+P351+P338P305+P354+P338
Trade & Regulatory
| HS Code | 29211990 |
| UN Number | 2733 |
| ADR Class | 3 |
| Packing Group | II |
| WGK (Germany) | 3 |
Other Names
3-Diethylamino-1-propyneN,N-diethylprop-2-yn-1-amineDEPN,N-Diethyl-2-propynylamineTIMTEC-BB SBB0087541-Diethylaminopropyne-23-(Diethylamino)propyne1-Diethylamino-2-propyne
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