Disulfiram

Disulfiram (CAS 97-77-8) is a tetraethylthiuram disulfide compound commercially known under trade names including Antabuse, Esperal, and Antadix, and abbreviated as DSF or DRAM. It belongs to the dithiocarbamate chemical family and is classified as a pharmaceutical intermediate with functional activity across multiple industrial sectors.

In rubber and polymer processing, disulfiram functions as a vulcanization accelerator and heat stabilizer by chelating metal ions that would otherwise catalyze oxidative degradation. In pharmaceutical manufacturing, it serves as the active substance in alcohol-aversion therapies by irreversibly inhibiting aldehyde dehydrogenase. Its antimicrobial and antioxidant properties also find application in food-contact and preservation formulations.

Disulfiram is supplied in crystalline powder and granule forms meeting Ph.Eur. and USP monograph specifications. It falls under REACH regulation (EC 202-607-8) and is classified under HS code 29303000. Procurement quantities and packaging formats are available on request from our European distribution network.