Ethyl bromoacetate
CAS 105-36-2
EC 203-290-9
Formula C4H7BrO2
MW 167 g/mol
Pharmaceutical Intermediates Personal Care & CosmeticsPharmaceuticals & Healthcare Preservation & BiocideFlavoring & Acidulant
Description
Ethyl bromoacetate (CAS 105-36-2, EC 203-290-9, C4H7BrO2) is a reactive halogenated ester also referred to as ethyl 2-bromoacetate, ethyl monobromoacetate, or ethyl α-bromoacetate. It carries no assigned E-code. It is registered under REACH and classified as a hazardous substance requiring appropriate handling controls.
In pharmaceutical synthesis, ethyl bromoacetate serves as an alkylating agent, introducing the acetate group into target molecules during active pharmaceutical ingredient production. In personal care formulations, it functions as a precursor in fragrance chemistry and contributes antimicrobial activity through its electrophilic reactivity with microbial cell components.
Ethyl bromoacetate is supplied in pharmaceutical-grade quality meeting relevant purity specifications for industrial synthesis applications. It is available in standard drum and IBC packaging formats and is subject to REACH registration requirements within the European Economic Area. Buyers should confirm grade suitability against their internal specification prior to ordering.
In pharmaceutical synthesis, ethyl bromoacetate serves as an alkylating agent, introducing the acetate group into target molecules during active pharmaceutical ingredient production. In personal care formulations, it functions as a precursor in fragrance chemistry and contributes antimicrobial activity through its electrophilic reactivity with microbial cell components.
Ethyl bromoacetate is supplied in pharmaceutical-grade quality meeting relevant purity specifications for industrial synthesis applications. It is available in standard drum and IBC packaging formats and is subject to REACH registration requirements within the European Economic Area. Buyers should confirm grade suitability against their internal specification prior to ordering.
Physical Properties
| Melting Point | -38 °C |
| Boiling Point | 168.5 °C |
| Density | 1.5032 g/cm³ @ Temp: 20 °C |
| Flash Point | 118 °F |
| Appearance | Ethyl bromoacetate is a clear, colorless to light-yellow liquid. |
| Color | Clear |
| Odor | Pungent odour |
| Form | Liquid |
| Water Solubility | Miscible with ethanol, acetone, benzene and ethyl ether. Immiscible with water. |
| Vapor Pressure | 2.6 mm Hg ( 25 °C) |
| Refractive Index | n 20/D 1.451(lit.) |
Safety & Handling (Learn More)
Danger GHS06 GHS02 GHS05
H
H226H300H310H318H330H300+H310+H330
P
P210P233P240P241P242P243P260P262P264P270P271P280P284P316P317P320P321P330P405P501P264+P265P301+P316P302+P352P304+P340P361+P364P370+P378P403+P233P403+P235P303+P361+P353P305+P354+P338
Trade & Regulatory
| HS Code | 29159080 |
| UN Number | 1603 |
| ADR Class | 6.1 |
| Packing Group | II |
| Storage Class | 3 - Flammable liquids |
| WGK (Germany) | 1 |
Other Names
Ethyl 2-BromoacetateAntolEthyl bromacetateEthyl α-bromoacetatebromoacetated’ethyleETHYL-2-BROMOETHANOATE
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