Fexofenadine hydrochloride
CAS 153439-40-8
EC 604-906-2
Formula C32H39NO4.ClH
MW 538.12 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & Cosmetics UV Protection & StabilizationPreservation & Biocide
Description
Fexofenadine hydrochloride (CAS 153439-40-8) is a selective histamine H1-receptor antagonist supplied as a pharmaceutical-grade active ingredient. Known commercially as Allegra, Telfast, and Fexofen, it carries no assigned E-code and is identified under EC 604-906-2 with HS code 2933399090.
In pharmaceutical formulations, it serves as the primary antihistamine active in oral allergy treatments, blocking peripheral H1 receptors without crossing the blood-brain barrier, which eliminates sedation as a side effect. In personal care applications, it functions as a UV absorber and skin conditioner, helping stabilise formulations against photodegradation while supporting antimicrobial preservation.
Supplied as an off-white crystalline powder conforming to Ph.Eur. and ICH Q7 GMP standards, this material is available in research quantities through to multi-kilogram industrial lots. REACH compliance documentation is available upon request, and packaging is provided under controlled conditions appropriate for active pharmaceutical ingredients.
In pharmaceutical formulations, it serves as the primary antihistamine active in oral allergy treatments, blocking peripheral H1 receptors without crossing the blood-brain barrier, which eliminates sedation as a side effect. In personal care applications, it functions as a UV absorber and skin conditioner, helping stabilise formulations against photodegradation while supporting antimicrobial preservation.
Supplied as an off-white crystalline powder conforming to Ph.Eur. and ICH Q7 GMP standards, this material is available in research quantities through to multi-kilogram industrial lots. REACH compliance documentation is available upon request, and packaging is provided under controlled conditions appropriate for active pharmaceutical ingredients.
Physical Properties
| Melting Point | 168.9 °C |
| Appearance | Off-White Crystalline Solid |
| Color | white to beige |
| Form | powder |
Safety & Handling (Learn More)
Danger GHS07 GHS08
H
H302H312H315H317H319H335H360
P
P203P261P264P270P271P272P280P317P318P319P321P330P405P501P264+P265P301+P317P302+P352P304+P340P332+P317P333+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 2933399090 |
| WGK (Germany) | 3 |
Other Names
FexoFexofenAllegraTelfastAlernexMDL 16455ATelfast BD
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