Fmoc-l-tryptophan

Fmoc-L-Tryptophan (CAS 35737-15-6) is a fluorenylmethoxycarbonyl-protected derivative of the amino acid L-tryptophan, commonly abbreviated as Fmoc-Trp-OH or Fmoc-L-Trp-OH. It carries no E-code designation. It serves as a building block in solid-phase peptide synthesis, where the Fmoc group protects the alpha-amine during chain assembly.

In solid-phase peptide synthesis, the Fmoc protecting group is removed stepwise under mild basic conditions, allowing controlled, sequential coupling of amino acid residues to form defined peptide sequences. This chemistry underpins the manufacture of research peptides, peptide-based active pharmaceutical ingredients, and diagnostic reagents where precise sequence integrity is required.

Fmoc-L-Tryptophan is supplied as a pharmaceutical-grade material compliant with REACH regulations and is available for procurement under HS code 29339900. It is typically offered in quantities ranging from laboratory scale to multi-kilogram lots, with documentation supporting GMP-aligned manufacturing processes.