SoleChem

Furosemide

CAS 54-31-9
EC 200-203-6
Formula C12H11ClN2O5S
MW 330.74 g/mol
Pharmaceutical Intermediates Pharmaceuticals & Healthcare Preservation & Biocide

Description

Furosemide (CAS 54-31-9) is a sulfonamide-derived loop diuretic active pharmaceutical ingredient, commercially known under trade names including Lasix and LB 502, and also referenced as frusemide or furosemid. It carries no assigned E-code and is classified within pharmaceutical intermediates under HS code 2935904000.

In pharmaceutical manufacturing, furosemide serves as the active substance in diuretic formulations targeting edema associated with cardiac, hepatic, and renal conditions. It acts by inhibiting the sodium-potassium-chloride cotransporter in the renal loop of Henle, blocking electrolyte reabsorption and promoting fluid excretion. It is also investigated as a functional component in antimicrobial and preservation research contexts.

Furosemide is supplied as a white to light yellow crystalline powder meeting Ph.Eur. and USP compendial standards. It is subject to REACH registration requirements within the European market. Packaging is available in quantities suited to pharmaceutical-grade procurement, with documentation supporting GMP-compliant supply chains.

Physical Properties

Melting Point 206 °C
Boiling Point 582.1±60.0 °C(Predicted)
Density 1.594 g/cm³ (solid)
Flash Point 11 °C
Appearance white to light yellow crystal powde
Color White to Off-White
Form powder
Water Solubility Soluble in acetone, DMF or methanol. Slightly soluble in water
Refractive Index 1.6580 (estimate)

Safety & Handling (Learn More)

Danger GHS07 GHS08
H
H315H319H335H351H360H361
P
P203P261P264P271P280P318P319P321P405P501P264+P265P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338

Trade & Regulatory

HS Code 2935904000
UN Number 1230
ADR Class 3
Packing Group II
Storage Class 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects
WGK (Germany) 3

Other Names

4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acidmethforylthiazidinedihydroflumethiazide4-chloro-N-furfuryl-5-sulfamoylanthranilic acidLasix"mita"LB 502Frusemide

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