Glucamine
CAS 488-43-7
EC 207-677-3
Formula C6H15NO5
MW 181.19 g/mol
Amines Pharmaceuticals & HealthcareFood & NutritionPersonal Care & Cosmetics pH Regulation & BufferingChelation & SequestrationHumectant & Moisturizing
Description
Glucamine (CAS 488-43-7), also known as D-Glucamine, Sorbitylamine, and 1-Amino-1-Deoxysorbitol, is a sugar-derived amine produced by the reductive amination of glucose. It carries no assigned E-code and is classified under HS code 29400090 within the broader amines category.
In pharmaceutical formulations, glucamine serves as a counterion in active pharmaceutical ingredient salt forms, improving solubility and bioavailability of acidic drug compounds. In personal care products, it functions as a pH buffer and humectant, stabilising formulation acidity while attracting and retaining moisture at the skin surface. Its chelating capacity also allows it to sequester metal ions that would otherwise degrade sensitive formulations.
Glucamine is supplied as a crystalline solid suitable for pharmaceutical and food-contact applications. Procurement teams should confirm compliance with REACH registration requirements and request documentation aligned with Ph.Eur. or FCC standards depending on the intended application. Certificates of Analysis and safety data sheets are available upon request.
In pharmaceutical formulations, glucamine serves as a counterion in active pharmaceutical ingredient salt forms, improving solubility and bioavailability of acidic drug compounds. In personal care products, it functions as a pH buffer and humectant, stabilising formulation acidity while attracting and retaining moisture at the skin surface. Its chelating capacity also allows it to sequester metal ions that would otherwise degrade sensitive formulations.
Glucamine is supplied as a crystalline solid suitable for pharmaceutical and food-contact applications. Procurement teams should confirm compliance with REACH registration requirements and request documentation aligned with Ph.Eur. or FCC standards depending on the intended application. Certificates of Analysis and safety data sheets are available upon request.
Physical Properties
| Melting Point | 127 °C |
| Boiling Point | 314.29°C (rough estimate) |
| Density | 1.3243 (rough estimate) |
| Flash Point | 230°C |
| Appearance | Crystalline Solid |
| Color | White to Pale Yellow |
| Form | Solid |
| Refractive Index | -7 ° (C=10, H2O) |
Safety & Handling (Learn More)
Warning GHS07
H
H315H319
P
P264P280P321P264+P265P302+P352P332+P317P337+P317P362+P364P305+P351+P338
Trade & Regulatory
| HS Code | 29400090 |
Other Names
(2R,3R,4R,5S)-6-aminohexane-1,2,3,4,5-pentolGLYCAMINED-GLUCAMINESORBITYLAMINE1-Amino-1-deoxysorbitol1-Amino-1-deoxyglucitol
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