Glycerol acetonide
CAS 100-79-8
EC 202-888-7
Formula C6H12O3
MW 132.16 g/mol
Heterocyclic Compounds Personal Care & CosmeticsPharmaceuticals & HealthcarePlastics & Polymers Preservation & BiocideAntioxidant & StabilizerCross-linking & CuringSolvent & Carrier
Description
Glycerol acetonide, also known as Solketal or GIE, is a cyclic acetal formed by the condensation of glycerol with acetone. It carries no E-code designation and is catalogued under CAS 100-79-8 and EC 202-888-7. It is also referenced in trade and technical literature as Glycerolacetone and Glycerol dimethylketal.
In pharmaceutical formulations, Solketal functions as a solvent and carrier that improves the solubility and bioavailability of active ingredients. In polymer systems, it acts as a crosslinker and heat stabilizer, forming covalent network structures that enhance thermal resistance. Its antimicrobial activity also makes it applicable as a preservation agent in personal care formulations.
Glycerol acetonide is supplied as a liquid and is available in standard industrial grades. It falls under REACH regulation and is classified under HS code 29329970 for import and export purposes. Procurement teams should confirm grade specifications against intended application requirements, particularly for pharmaceutical or cosmetic use.
In pharmaceutical formulations, Solketal functions as a solvent and carrier that improves the solubility and bioavailability of active ingredients. In polymer systems, it acts as a crosslinker and heat stabilizer, forming covalent network structures that enhance thermal resistance. Its antimicrobial activity also makes it applicable as a preservation agent in personal care formulations.
Glycerol acetonide is supplied as a liquid and is available in standard industrial grades. It falls under REACH regulation and is classified under HS code 29329970 for import and export purposes. Procurement teams should confirm grade specifications against intended application requirements, particularly for pharmaceutical or cosmetic use.
Physical Properties
| Melting Point | -26.4 °C |
| Boiling Point | 188 °C |
| Density | 1.06 g/cm³ |
| Flash Point | 176 °F |
| Appearance | clear colourless liquid |
| Color | Clear colorless |
| Form | Liquid |
| Water Solubility | miscible |
| Vapor Pressure | 34Pa at 20℃ |
| Refractive Index | n 20/D 1.434 |
| pH | 4.0-7.5 (H2O) |
| Log P | 0.3 at 20℃ |
Safety & Handling (Learn More)
Warning GHS07 GHS09
H
H315H319H411
P
P264P273P280P321P391P501P264+P265P302+P352P332+P317P337+P317P362+P364P305+P351+P338
Trade & Regulatory
| HS Code | 29329970 |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 2 |
Other Names
Solketal1,2-Isopropylideneglycerol1,2-O-IsopropylideneglycerolDL-1,2-Isopropylideneglycerol(2,2-dimethyl-1,3-dioxolan-4-yl)methanolGIEGlycerolacetoneGlycerol dimethylketalACETONE GLYCERINE KETAL
Related Products
Raw Materials
Derivatives
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