α-Glycylglycine
CAS 556-50-3
EC 209-127-8
Formula C4H8N2O3
MW 132.12 g/mol
Amino Acids & Peptides Personal Care & CosmeticsPharmaceuticals & Healthcare Humectant & MoisturizingpH Regulation & Buffering
Description
α-Glycylglycine (CAS 556-50-3), also known as diglycine, Gly-Gly, or Gly2, is a dipeptide formed from two glycine residues linked by a peptide bond. It carries no E-code designation. It is commercially available under abbreviations including GLY-GLY and GLY-GLY-OH.
In personal care formulations, diglycine functions as a humectant and skin conditioner by attracting and retaining moisture within the stratum corneum, while its buffering capacity helps stabilise product pH in the range relevant to skin compatibility. In pharmaceutical applications, it serves as a buffer component in injectable formulations and protein stabilisation systems.
α-Glycylglycine is supplied in solid form and is available in cosmetic and pharmaceutical grades. It falls under REACH registration requirements for EU market supply and is classified under HS code 29241900. Procurement teams should confirm grade-specific documentation, including certificate of analysis and safety data sheet, prior to ordering.
In personal care formulations, diglycine functions as a humectant and skin conditioner by attracting and retaining moisture within the stratum corneum, while its buffering capacity helps stabilise product pH in the range relevant to skin compatibility. In pharmaceutical applications, it serves as a buffer component in injectable formulations and protein stabilisation systems.
α-Glycylglycine is supplied in solid form and is available in cosmetic and pharmaceutical grades. It falls under REACH registration requirements for EU market supply and is classified under HS code 29241900. Procurement teams should confirm grade-specific documentation, including certificate of analysis and safety data sheet, prior to ordering.
Physical Properties
| Melting Point | 215 °C (decomp) |
| Boiling Point | 267.18°C (rough estimate) |
| Density | 0.9938 g/cm³ @ Temp: 45.00 °C |
| Appearance | White crystals |
| Color | White |
| Form | Solid |
| Water Solubility | SOLUBLE IN HOT WATER |
| Vapor Pressure | 0.058Pa at 20-50℃ |
| Refractive Index | 1.4880 (estimate) |
| pH | 4.5-6.0 (20℃, 1M in H2O) |
| Log P | -0.92 at 25℃ and pH6 |
Safety & Handling (Learn More)
Warning GHS07
H
H319
P
P280P264+P265P337+P317P305+P351+P338
Trade & Regulatory
| HS Code | 29241900 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
2-[(2-aminoacetyl)amino]acetic acidGly2Gly-GlyDiglycineGLY-GLY-OHDiglycocollH-GLY-GLY-OH
Related Products
Raw Materials
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