Guanosine
CAS 118-00-3
EC 204-227-8
Formula C10H13N5O5
MW 283.24 g/mol
Nucleosides & Nucleotides Personal Care & CosmeticsBiotechnology & Life SciencesPharmaceuticals & Healthcare Humectant & MoisturizingSurface Modification & Wetting
Description
Guanosine (CAS 118-00-3), also known by the trade names Vernine and Guanine Riboside, is a naturally occurring purine nucleoside composed of guanine linked to a ribose sugar. It carries no assigned E-code and is catalogued under EC 204-227-8 with molecular formula C10H13N5O5.
In personal care formulations, guanosine functions as a humectant and skin conditioner by attracting and retaining moisture at the skin surface, supporting barrier integrity. In pharmaceutical and biotechnology applications, it serves as a biochemical building block and reference standard, contributing to nucleotide synthesis pathways and cellular energy metabolism research.
Guanosine is supplied as a crystalline powder and is available in research and commercial grades suitable for cosmetic and pharmaceutical manufacturing. It falls under REACH regulation and is classified under HS code 29349990. Procurement teams should confirm grade specifications against Ph.Eur. or equivalent pharmacopoeial standards depending on the intended application.
In personal care formulations, guanosine functions as a humectant and skin conditioner by attracting and retaining moisture at the skin surface, supporting barrier integrity. In pharmaceutical and biotechnology applications, it serves as a biochemical building block and reference standard, contributing to nucleotide synthesis pathways and cellular energy metabolism research.
Guanosine is supplied as a crystalline powder and is available in research and commercial grades suitable for cosmetic and pharmaceutical manufacturing. It falls under REACH regulation and is classified under HS code 29349990. Procurement teams should confirm grade specifications against Ph.Eur. or equivalent pharmacopoeial standards depending on the intended application.
Physical Properties
| Melting Point | 239 °C (decomp) |
| Boiling Point | 425.8°C (rough estimate) |
| Density | 1.3790 (rough estimate) |
| Appearance | Crystalline |
| Color | White to light yellow |
| Odor | Odorless |
| Form | Powder |
| Water Solubility | 0.75 g/L (25 ºC) |
| Refractive Index | -76 ° (C=1, 1mol/L NaOH) |
| pH | 2.14；9.03 |
| Log P | -2.331 (est) |
Safety & Handling (Learn More)
Danger GHS06
H
H301
P
P264P270P321P330P405P501P301+P316
Trade & Regulatory
| HS Code | 29349990 |
| UN Number | 2811 |
| ADR Class | 6.1 |
| Packing Group | III |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
GuoVernineD-GUANOSINEDL-GuanosineGUANINE RIBOSIDEInosine, 2-amino-Guanine ribonucleoside
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