SoleChem

Hexamidine diisethionate

CAS 659-40-5
EC 211-533-5
Formula C20H26N4O2.2C2H6O4S
MW 606.714 g/mol
Surfactants Personal Care & CosmeticsPharmaceuticals & Healthcare Preservation & BiocideEmulsification & DispersionCatalysis

Description

Hexamidine diisethionate (CAS 659-40-5) is a synthetic diamidine compound supplied as a white to off-white hygroscopic powder. It is also known under the trade designations 2535RP, RP-2535, HD-100, and HP-100. No E-code applies to this substance.

In cosmetic and topical pharmaceutical formulations, hexamidine diisethionate functions as a broad-spectrum preservative by disrupting microbial cell membranes, inhibiting bacterial and fungal growth at low concentrations. It also acts as an emulsification aid, stabilising oil-in-water systems through its amphiphilic character, and finds use as a catalyst in select chemical synthesis processes.

This material is available in pharmaceutical and cosmetic grades and falls under REACH registration requirements for EU supply. Compliance documentation including SDS and CoA is available upon request. Standard packaging formats include fibre drums and multi-layer bags; custom quantities can be arranged for qualified buyers.

Physical Properties

Melting Point 246-247° (dec)
Density 671[at 20℃]
Appearance White or slightly yellow powder, hygroscopic
Form neat
Water Solubility 48.2g/L at 20℃
Vapor Pressure 0Pa at 20℃
Log P 4.47 at 25℃

Safety & Handling (Learn More)

Warning GHS07 GHS09
H
H302H319H400H410H411
P
P264P270P273P280P330P391P501P264+P265P301+P317P337+P317P305+P351+P338

Trade & Regulatory

Storage Class 11 - Combustible Solids
WGK (Germany) 3

Other Names

HD-100HP-1002535RPRP 2535SymCalminEsomedinaDesomedine

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