SoleChem

Histidine

CAS 71-00-1
EC 200-745-3
Formula C6H9N3O2
MW 155.15 g/mol
Amino Acids & Peptides Personal Care & CosmeticsFood & NutritionPharmaceuticals & Healthcare Antioxidant & StabilizerHumectant & MoisturizingpH Regulation & Buffering

Description

Histidine (CAS 71-00-1) is a naturally occurring amino acid commercially identified by the abbreviations L-HIS, H-HIS-OH, and H-L-HIS-OH, and assigned FEMA number 3694. It carries no E-code designation. It is sourced through fermentation and is available in its biologically active L-form.

In personal care formulations, histidine functions as a film-forming hair and skin conditioner while its imidazole side chain provides pH buffering capacity across a physiologically relevant range. In food and nutraceutical applications, it acts as a humectant and antioxidant, chelating metal ions that would otherwise catalyse lipid oxidation.

Histidine is supplied as a white crystalline powder meeting Ph.Eur., USP, and FCC grade specifications, supporting pharmaceutical, cosmetic, and food-grade procurement requirements. The substance is registered under REACH (EC 200-745-3) and classified under HS code 29332990. Standard packaging includes fibre drums and multi-layer bags.

Physical Properties

Melting Point 287 °C (decomp)
Boiling Point 278.95°C (rough estimate)
Density 1.309 g/cm³
Appearance White crystalline powder
Color White to off-white or pale yellow
Odor odorless
Form powder
Water Solubility 41.6 g/L (25 ºC)
Refractive Index 13 ° (C=11, 6mol/L HCl)
pH 7.0-8.0 (25℃, 0.1M in H2O)
Log P -1.27

Safety & Handling (Learn More)

Warning GHS07
H
H302H315H319H332
P
P261P264P270P271P280P317P321P330P501P264+P265P301+P317P302+P352P304+P340P332+P317P337+P317P362+P364P305+P351+P338

Trade & Regulatory

HS Code 29332990
Storage Class 11 - Combustible Solids
WGK (Germany) 2

Other Names

(2S)-2-amino-3-(1H-imidazol-5-yl)propanoic acidHisL-HistidineL-HISH-HIS-OHH-L-HIS-OH

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