Irbesartan

Irbesartan (CAS 138402-11-6, EC 604-078-2) is a pharmaceutical active ingredient belonging to the angiotensin II receptor antagonist class, primarily developed for cardiovascular indications. It is commercially recognized under the trade names Aprovel, Avapro, and Karvea. No E-code designation applies to this substance.

In pharmaceutical manufacturing, irbesartan serves as the active component in antihypertensive drug formulations, where it functions by selectively blocking AT1 angiotensin II receptors to reduce vascular resistance. Secondary research applications explore its antimicrobial and skin-conditioning properties, particularly in topical formulation development within personal care contexts.

Irbesartan is supplied as a pharmaceutical-grade crystalline powder, manufactured in compliance with Ph.Eur. monograph standards and subject to REACH registration requirements within the EU. Procurement quantities typically range from laboratory scale to bulk industrial volumes. Buyers should confirm GMP certification status and country-of-origin documentation prior to sourcing, classified under HS code 29332900.