Isobutylparaben
CAS 4247-02-3
EC 224-208-8
Formula C11H14O3
MW 194.23 g/mol
Pharmaceutical Intermediates Personal Care & CosmeticsPharmaceuticals & HealthcareFood & Nutrition Preservation & Biocide
Description
Isobutylparaben (CAS 4247-02-3) is a paraben-ester preservative derived from p-hydroxybenzoic acid, also known as isobutyl 4-hydroxybenzoate or isobutyl p-hydroxybenzoate. It carries no assigned E-code and is not approved as a food additive in the EU. It is classified under HS code 29182900.
In cosmetic and topical pharmaceutical formulations, isobutylparaben inhibits microbial growth by disrupting cell membrane function and interfering with enzyme activity in bacteria and fungi. It is used in creams, lotions, and ointments, typically in combination with other parabens to broaden the antimicrobial spectrum across a wider range of organisms.
Isobutylparaben is available in pharmaceutical-grade form and is subject to REACH registration requirements for EU supply. Suppliers typically offer it in solid form, packaged in fiber drums or polyethylene-lined bags. Procurement teams should confirm compliance documentation, including safety data sheets and certificates of analysis, prior to sourcing.
In cosmetic and topical pharmaceutical formulations, isobutylparaben inhibits microbial growth by disrupting cell membrane function and interfering with enzyme activity in bacteria and fungi. It is used in creams, lotions, and ointments, typically in combination with other parabens to broaden the antimicrobial spectrum across a wider range of organisms.
Isobutylparaben is available in pharmaceutical-grade form and is subject to REACH registration requirements for EU supply. Suppliers typically offer it in solid form, packaged in fiber drums or polyethylene-lined bags. Procurement teams should confirm compliance documentation, including safety data sheets and certificates of analysis, prior to sourcing.
Physical Properties
| Melting Point | 74-77 °C |
| Boiling Point | 302.3±15.0 °C(Predicted) |
| Density | 1.105±0.06 g/cm3(Predicted) |
| Color | White |
| Form | neat |
| Water Solubility | Insoluble in water. |
| Vapor Pressure | 0.001Pa at 20℃ |
| Log P | 3.43 at 23℃ |
Safety & Handling (Learn More)
Danger GHS05 GHS07
H
H315H318
P
P264P280P317P321P264+P265P302+P352P332+P317P362+P364P305+P354+P338
Trade & Regulatory
| HS Code | 29182900 |
| UN Number | 3077 |
| ADR Class | 9 |
| Packing Group | III |
| Storage Class | 13 - Non Combustible Solids |
| WGK (Germany) | 2 |
Other Names
2-methylpropyl 4-hydroxybenzoateIsobutyl p-hydroxybenzoateISOBUTYL 4-HYDROXYBENZOATEiso-Butyl p-hydroxybenzoatep-oxybenzoesaureisobutylester2-methylpropyl4-hydroxybenzoate
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