Isophthaloyl chloride

Isophthaloyl chloride (CAS 99-63-8), also known as isophthalyl chloride, m-phthaloyl chloride, and isophthalyl dichloride, is an aromatic diacid chloride derived from isophthalic acid. It carries no assigned E-code and is classified under HS code 29173940 for customs and trade purposes.

In polymer synthesis, isophthaloyl chloride reacts with diamines or diols to form high-performance polyamides and polyesters, contributing thermal stability and mechanical strength to engineering plastics and technical textiles. In pharmaceutical and personal care formulations, it functions as a reactive intermediate for antimicrobial agents and skin-conditioning compounds, where its acyl chloride groups enable precise bond formation with target molecules.

Isophthaloyl chloride is supplied as a white crystalline mass in technical and high-purity grades, with availability subject to REACH registration requirements for European procurement. Packaging typically follows standard protocols for moisture-sensitive acyl chlorides. Buyers should confirm grade specifications and SDS documentation prior to ordering.