k1-Phytonadione
CAS 84-80-0
EC 201-564-2
Formula C31H46O2
MW 452.71 g/mol
Vitamins & Nutrients Personal Care & CosmeticsPharmaceuticals & HealthcareFood & Nutrition Flavoring & AcidulantAntioxidant & Stabilizer
Description
K1-Phytonadione (CAS 84-80-0) is a naturally occurring form of Vitamin K1, also known under trade names including Mephyton, Mono-Kay, Kativ N, and Kephton. It carries no assigned E-code and is classified under the Vitamins & Nutrients category with molecular formula C31H46O2.
In pharmaceutical formulations, Phytonadione acts as a cofactor supporting coagulation cascade proteins, making it relevant in injectable and oral drug products. In personal care applications, it functions as an antioxidant that helps stabilize formulations against oxidative degradation, and it is also used as a fragrance component in select cosmetic preparations.
K1-Phytonadione is available in pharmaceutical-grade form meeting Ph.Eur. and USP standards, as well as food-grade specifications aligned with FCC requirements. It is subject to REACH registration and classified under HS code 29369000. Packaging formats typically include amber glass vials or sealed containers to protect against light-induced degradation.
In pharmaceutical formulations, Phytonadione acts as a cofactor supporting coagulation cascade proteins, making it relevant in injectable and oral drug products. In personal care applications, it functions as an antioxidant that helps stabilize formulations against oxidative degradation, and it is also used as a fragrance component in select cosmetic preparations.
K1-Phytonadione is available in pharmaceutical-grade form meeting Ph.Eur. and USP standards, as well as food-grade specifications aligned with FCC requirements. It is subject to REACH registration and classified under HS code 29369000. Packaging formats typically include amber glass vials or sealed containers to protect against light-induced degradation.
Physical Properties
| Melting Point | -20 °C |
| Boiling Point | 140-145 °C @ Press: 1 x 10-3 Torr |
| Density | 0.964 g/cm³ @ Temp: 25 °C |
| Flash Point | >230 °F |
| Appearance | Phylloquinone is an odorless yellow viscous oil or crystals. |
| Color | Yellow to Dark Yellow |
| Odor | odorless |
| Form | viscous liquid |
| Water Solubility | Miscible with dehydrated alcohol, acetone, petroleum ether, hexane, dioxane, chloroform, ether, benzene and vegetable oils. Immiscible with water. |
| Refractive Index | n 20/D 1.527(lit.) |
| Log P | 10.305 (est) |
Safety & Handling (Learn More)
Warning GHS07
H
H317H413
P
P261P272P273P280P321P501P302+P352P333+P317P362+P364
Trade & Regulatory
| HS Code | 29369000 |
| UN Number | 1170 |
| Packing Group | II |
| Storage Class | 10 - Combustible liquids |
| WGK (Germany) | 2 |
Other Names
K-JectKativ NKephton(E)-phytonadioneMono-KayMephytonVitamin K1PHYTONADIONEPhylloquinone
Related Products
Raw Materials
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