L-Isoleucine
CAS 73-32-5
EC 200-798-2
Formula C6H13NO2
MW 131.17 g/mol
Amino Acids & Peptides Personal Care & CosmeticsPharmaceuticals & HealthcareFood & Nutrition Humectant & MoisturizingpH Regulation & BufferingAntioxidant & Stabilizer
Description
L-Isoleucine (CAS 73-32-5, EC 200-798-2) is a branched-chain essential amino acid commonly abbreviated as Ile or ILE and referenced in formulation contexts as H-ILE-OH or H-L-ILE-OH. It carries no E-code designation. It belongs to the amino acids and peptides category with the molecular formula C6H13NO2.
In personal care formulations, L-Isoleucine functions as a humectant and skin conditioner by attracting and retaining moisture within the stratum corneum, while its buffering capacity helps stabilise product pH in aqueous systems. In pharmaceutical and nutritional applications, it contributes to antioxidant stability and serves as a skin protectant active in topical preparations.
L-Isoleucine is available in food-grade (FCC), pharmaceutical-grade (Ph.Eur.), and cosmetic-grade specifications as a white crystalline powder. The substance is registered under REACH and supplied with full EU regulatory documentation. Standard packaging includes fibre drums and multi-layer bags; HS code 29224995 applies for import classification.
In personal care formulations, L-Isoleucine functions as a humectant and skin conditioner by attracting and retaining moisture within the stratum corneum, while its buffering capacity helps stabilise product pH in aqueous systems. In pharmaceutical and nutritional applications, it contributes to antioxidant stability and serves as a skin protectant active in topical preparations.
L-Isoleucine is available in food-grade (FCC), pharmaceutical-grade (Ph.Eur.), and cosmetic-grade specifications as a white crystalline powder. The substance is registered under REACH and supplied with full EU regulatory documentation. Standard packaging includes fibre drums and multi-layer bags; HS code 29224995 applies for import classification.
Physical Properties
| Melting Point | 285.5 °C (decomp) |
| Boiling Point | 225.8±23.0 °C(Predicted) |
| Density | 1.2930 (estimate) |
| Flash Point | 168-170°C |
| Appearance | White crystalline powder |
| Color | White to Off-white |
| Odor | odorless |
| Form | powder |
| Water Solubility | 41.2 g/L (50 ºC) |
| Refractive Index | 40.5 ° (C=4, 6mol/L HCl) |
| pH | 5.5-6.5 (40g/l, H2O, 20℃) |
| Log P | 0.80 |
Trade & Regulatory
| HS Code | 29224995 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
(2S,3S)-2-amino-3-methylpentanoic acidIleL-IleH-ILE-OHIsoleucineH-L-ILE-OHISOLEUCINE, L-
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Raw Materials
Derivatives
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