L-Serine
CAS 56-45-1
EC 200-274-3
Formula C3H7NO3
MW 105.09 g/mol
Amino Acids & Peptides Personal Care & CosmeticsFood & NutritionPharmaceuticals & Healthcare Humectant & MoisturizingpH Regulation & BufferingAntioxidant & Stabilizer
Description
L-Serine (CAS 56-45-1) is a naturally occurring non-essential amino acid with the molecular formula C3H7NO3, commercially identified by the abbreviations Ser, L-Ser, and H-Ser-OH. It carries no assigned E-code and is not classified as a food additive under EU regulation. It is produced via fermentation or chemical synthesis.
In personal care formulations, L-Serine functions as a humectant and skin conditioner by binding water within the stratum corneum, improving moisture retention at the cellular level. In pharmaceutical and nutraceutical applications, it serves as a buffering agent and antioxidant, stabilising active compounds against oxidative degradation across a defined pH range.
L-Serine is available in pharmaceutical grade (Ph.Eur., USP) and food grade (FCC) specifications, supporting compliance across regulated markets. The substance is registered under REACH and supplied as a white crystalline powder in quantities from kilogram packs to multi-tonne bulk. HS code 29225000 applies for EU import and export classification.
In personal care formulations, L-Serine functions as a humectant and skin conditioner by binding water within the stratum corneum, improving moisture retention at the cellular level. In pharmaceutical and nutraceutical applications, it serves as a buffering agent and antioxidant, stabilising active compounds against oxidative degradation across a defined pH range.
L-Serine is available in pharmaceutical grade (Ph.Eur., USP) and food grade (FCC) specifications, supporting compliance across regulated markets. The substance is registered under REACH and supplied as a white crystalline powder in quantities from kilogram packs to multi-tonne bulk. HS code 29225000 applies for EU import and export classification.
Physical Properties
| Melting Point | 228 °C (decomp) |
| Boiling Point | 197.09°C (rough estimate) |
| Density | 1.6 g/cm³ @ Temp: 22 °C |
| Flash Point | 150°C |
| Appearance | White crystalline powder |
| Color | White |
| Odor | wh. cryst. or cryst. powd., odorless, sweet taste |
| Form | powder |
| Water Solubility | 250 g/L (20 ºC) |
| Refractive Index | 1.4368 (estimate) |
| pH | 5-6 (100g/l, H2O, 20℃) |
| Log P | -1.580 |
Trade & Regulatory
| HS Code | 29225000 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
(2S)-2-amino-3-hydroxypropanoic acidSerL-SerSerineH-SER-OH(S)-SerineH-L-SER-OHSerine, L-
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Raw Materials
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