Lamivudine
CAS 134678-17-4
EC 603-844-3
Formula C8H11N3O3S
MW 229.26 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & Cosmetics Preservation & BiocideHumectant & Moisturizing
Description
Lamivudine (CAS 134678-17-4) is a synthetic nucleoside analogue developed as an antiviral pharmaceutical active, also referenced under the designations GR 109714X, BCH-189, and trade names including Heptovir. It carries no assigned E-code. The compound is classified as a pharmaceutical intermediate within regulated API supply chains.
In pharmaceutical manufacturing, lamivudine functions as a reverse transcriptase inhibitor, blocking viral RNA replication at the enzymatic level, and serves as a key active ingredient in antiviral drug formulations. In personal care research, it is investigated as an antimicrobial and skin-conditioning agent, where its biocidal mechanism targets microbial proliferation within formulations.
Lamivudine is supplied as a white crystalline powder meeting Ph.Eur. and ICH Q7 GMP standards applicable to pharmaceutical-grade intermediates. It falls under HS code 29349900 and is subject to REACH registration requirements within the EU. Packaging formats are available on request to meet specific handling and storage protocols.
In pharmaceutical manufacturing, lamivudine functions as a reverse transcriptase inhibitor, blocking viral RNA replication at the enzymatic level, and serves as a key active ingredient in antiviral drug formulations. In personal care research, it is investigated as an antimicrobial and skin-conditioning agent, where its biocidal mechanism targets microbial proliferation within formulations.
Lamivudine is supplied as a white crystalline powder meeting Ph.Eur. and ICH Q7 GMP standards applicable to pharmaceutical-grade intermediates. It falls under HS code 29349900 and is subject to REACH registration requirements within the EU. Packaging formats are available on request to meet specific handling and storage protocols.
Physical Properties
| Melting Point | 160-162 °C |
| Boiling Point | 475.4±55.0 °C(Predicted) |
| Density | 1.73±0.1 g/cm3(Predicted) |
| Flash Point | 9°C |
| Appearance | White Crystalline Powder |
| Color | white to beige |
| Form | powder |
| Water Solubility | 70g/L(temperature not stated) |
| Refractive Index | -142 ° (C=1, MeOH) |
Safety & Handling (Learn More)
Warning GHS07 GHS08
H
H315H319H335H361H373
P
P203P260P261P264P271P280P318P319P321P405P501P264+P265P302+P352P304+P340P332+P317P337+P317P362+P364P403+P233P305+P351+P338
Trade & Regulatory
| HS Code | 29349900 |
| UN Number | 1230 |
| Packing Group | II |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
3TCHeptovirLamivudin(-)-2¢GR 109714X(-)NGPB-21(-)-BCH-189(-)-BCH 189BCH 189, (-)-
Related Products
Raw Materials
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