Lidocaine
CAS 137-58-6
EC 205-302-8
Formula C14H22N2O
MW 262.32 g/mol
Pharmaceutical Intermediates Pharmaceuticals & HealthcarePersonal Care & Cosmetics Preservation & BiocideUV Protection & Stabilization
Description
Lidocaine (CAS 137-58-6) is a synthetic amino amide compound known under trade names including Xylocaine, Isicaine, Leostesin, and Maricaine. It carries no assigned E-code and is classified under pharmaceutical intermediates, with the molecular formula C14H22N2O.
In pharmaceutical formulations, lidocaine functions as a local anesthetic by blocking voltage-gated sodium channels, interrupting nerve signal transmission. In personal care applications, it acts as a skin protectant and conditioner, and its UV-absorbing properties make it relevant in topical products requiring photostability support. Antimicrobial activity also supports its use in preservation-focused formulations.
Lidocaine is available as a white crystalline powder in pharmaceutical-grade quality conforming to Ph.Eur. and USP monographs, with REACH compliance applicable for EU supply. It is classified under HS code 29242990. Standard packaging formats include fiber drums and double-lined polyethylene bags, with documentation available to support regulated procurement processes.
In pharmaceutical formulations, lidocaine functions as a local anesthetic by blocking voltage-gated sodium channels, interrupting nerve signal transmission. In personal care applications, it acts as a skin protectant and conditioner, and its UV-absorbing properties make it relevant in topical products requiring photostability support. Antimicrobial activity also supports its use in preservation-focused formulations.
Lidocaine is available as a white crystalline powder in pharmaceutical-grade quality conforming to Ph.Eur. and USP monographs, with REACH compliance applicable for EU supply. It is classified under HS code 29242990. Standard packaging formats include fiber drums and double-lined polyethylene bags, with documentation available to support regulated procurement processes.
Physical Properties
| Melting Point | 68.5 °C |
| Boiling Point | 159-160 °C @ Press: 2 Torr |
| Density | 1.026 g/cm³ |
| Flash Point | 9°C |
| Appearance | solid |
| Color | White to slightly yellow |
| Form | powder |
| Water Solubility | practically insoluble |
| Refractive Index | 1.5110 (estimate) |
| Log P | 2.440 |
Safety & Handling (Learn More)
Warning GHS07 GHS08
H
H302H317H362H370H372
P
P203P260P261P263P264P270P272P280P318P319P321P330P405P501P301+P317P302+P352P308+P316P333+P317P362+P364
Trade & Regulatory
| HS Code | 29242990 |
| Storage Class | 11 - Combustible Solids |
| WGK (Germany) | 3 |
Other Names
2-(diethylamino)-N-(2,6-dimethylphenyl)acetamidexylocainelignocaineIsicaineLeostesinMaricaineLIDOCAINE-D6
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